Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 4/20 | 0.49 |
| ▸ | MMP9 | P14780 | 4/20 | 0.49 |
| ▸ | MMP12 | P39900 | 4/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MMP14 | P50281 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31225690 | 0.77 | TAAR1 (0.45) | HPGDSMN1; SMN2LMNAMAPK1L3MBTL1 | |
| SCHEMBL3045866 | 0.77 | LMNA (0.45) | MMP2MMP9MMP12CYP2C9CYP2C19 | |
| SCHEMBL5286051 | 0.76 | SMN1; SMN2 (0.53) | HPGDSMN1; SMN2L3MBTL1ALDH1A1KMT2A | |
| SCHEMBL31225781 | 0.76 | AKR1B1 (0.52) | SMN1; SMN2CYP2D6L3MBTL1ATM | |
| SCHEMBL3765157 | 0.75 | HPGD (0.78) | MMP2MMP9MMP12CYP2C9CYP2C19 | |
| SCHEMBL6937307 | 0.74 | SMN1; SMN2 (0.67) | HPGDSMN1; SMN2MAPK1L3MBTL1ALDH1A1 | |
| SCHEMBL3640100 | 0.72 | CYP2C9 (0.72) | MMP2MMP9MMP12CYP2C9CYP2C19 | |
| SCHEMBL10964197 | 0.71 | ALDH1A1 (0.39) | HPGDSMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL6932450 | 0.71 | MMP2 (0.54) | MMP2MMP9MMP12CYP2C9CYP2C19 | |
| SCHEMBL5283083 | 0.71 | HTR1A (0.48) | HPGDSMN1; SMN2LMNAMAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007001335-A2 | RAMOPLANIN DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | VICURON PHARMACEUTICALS INC. (US) | 2007-01-04 | — | — | WO | disclosed |
| US-20060211603-A1 | Ramoplanin derivatives possessing antibacterial activity | VICURON PHARMACEUTICALS INC. (US) | 2006-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060211603-A1 | Ramoplanin derivatives possessing antibacterial activity | CLSPN, LMAN2, RPN2 | MMP2 1558/4885MMP9 2358/4885MMP12 1035/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.