Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 1/20 | 0.54 |
| ▸ | TACR3 | P29371 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | STAT3 | P40763 | 1/20 | 0.46 |
| ▸ | ECE1 | P42892 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5062062 | 0.81 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2LMNAHTTMAPT | |
| SCHEMBL5057786 | 0.81 | CNR1 (0.48) | LMNA | |
| SCHEMBL2188126 | 0.81 | ALDH1A1 (0.50) | TACR1TACR3ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL14432821 | 0.78 | HDAC1 (0.44) | TACR1TACR3ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL2186733 | 0.76 | KDM4E (0.48) | ALDH1A1KMT2AKDM4EBRD4POLB | |
| SCHEMBL1228585 | 0.75 | FAAH (0.42) | ALDH1A1LMNAHTTKMT2AMEN1 | |
| SCHEMBL27679675 | 0.74 | LMNA (0.50) | ALDH1A1SMN1; SMN2LMNAMAPTKMT2A | |
| SCHEMBL1043735 | 0.74 | MEN1 (0.54) | ALDH1A1SMN1; SMN2LMNAHTTMAPT | |
| SCHEMBL13162592 | 0.74 | EPHX2 (0.39) | SMN1; SMN2LMNAMAPT | |
| SCHEMBL1851840 | 0.74 | KMT2A (0.73) | TACR1TACR3ALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1832586-A1 | Thiazole-piperidine derivatives in treatment of diseases of liver and the pancreas | Oridis Biomed Forschungs- und Entwicklungs GmbH (AT) | 2007-09-12 | — | — | EP | disclosed |