Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3127644 | 0.95 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2CYP1A2CYP2C19MEN1 | |
| SCHEMBL5379722 | 0.91 | MAPK1 (0.46) | ALDH1A1SMN1; SMN2CYP1A2CYP2C19MEN1 | |
| SCHEMBL5378101 | 0.88 | GAA (0.38) | ALDH1A1SMN1; SMN2CYP1A2CYP2C19MEN1 | |
| SCHEMBL2824611 | 0.81 | SLC9A1 (0.41) | ALDH1A1CYP1A2KMT2ATSHRHSD17B10 | |
| SCHEMBL44479 | 0.81 | SLC9A1 (0.41) | ALDH1A1CYP1A2KMT2ATSHRHSD17B10 | |
| SCHEMBL1941412 | 0.81 | SLC9A1 (0.41) | ALDH1A1CYP1A2KMT2ATSHRHSD17B10 | |
| SCHEMBL5332213 | 0.80 | SLC9A1 (0.40) | ALDH1A1CYP1A2KMT2ATSHRHSD17B10 | |
| SCHEMBL1187391 | 0.78 | SMN1; SMN2 (0.40) | ALDH1A1SMN1; SMN2CYP1A2CYP2C19MEN1 | |
| SCHEMBL1395480 | 0.75 | POLB (0.54) | ALDH1A1CYP1A2KMT2ATSHRHSD17B10 | |
| SCHEMBL153586 | 0.75 | TUBB4A (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 378 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025119223-A1 | METHOD FOR SYNTHESIZING AMANITIN AND DERIVATIVE THEREOF | 上海皓元生物医药科技有限公司 | 2025-06-12 | — | — | WO | claimed |
| US-20240351989-A1 | PROCESS FOR THE PREPARATION OF OLAPARIB, AND CRYSTALLINE FORM THEREOF | ALIVUS LIFE SCIENCES LIMITED (IN) | 2024-10-24 | — | — | US | claimed |
| EP-4384501-A1 | PROCESS FOR THE PREPARATION OF OLAPARIB, AND CRYSTALLINE FORM THEREOF | Glenmark Life Sciences Limited (IN) | 2024-06-19 | — | — | EP | claimed |
| WO-2023017393-A1 | PROCESS FOR THE PREPARATION OF OLAPARIB, AND CRYSTALLINE FORM THEREOF | GLENMARK LIFE SCIENCES LIMITED (IN) | 2023-02-16 | — | — | WO | claimed |
| US-10322104-B2 | Disulfur bridge linkers for conjugation of a cell-binding molecule | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2019-06-18 | — | — | US | claimed |
| US-10232051-B2 | Acetylenedicarboxyl linkers and their uses in specific conjugation of a cell-binding molecule | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2019-03-19 | — | — | US | claimed |
| US-9839687-B2 | Acetylenedicarboxyl linkers and their uses in specific conjugation of a cell-binding molecule | SUZHOU M-CONJ BIOTECH CO., LTD. (CN) | 2017-12-12 | — | — | US | claimed |
| EP-2069323-B1 | PROCESSES FOR THE PREPARATION OF N-(2-ACETYL-4,6-DIMETHYLPHENYL)-3-{[(3,4 DIMETHYL-5-ISOXAZOLYL)AMINO]SULFONYL}-2-THIOPHENECARBOXAMIDE | ENCYSIVE PHARMACEUTICALS INC (US) | 2010-05-05 | — | — | EP | claimed |
| US-20090318704-A1 | Processes for the Preparation of N-(2-Acetyl-4,6-Dimethylphenyl)-3--2-Thiophenecarboxamide | REICHWEIN JOHN F | 2009-12-24 | — | — | US | claimed |
| EP-2069323-A1 | PROCESSES FOR THE PREPARATION OF N-(2-ACETYL-4,6-DIMETHYLPHENYL)-3-{[(3,4 DIMETHYL-5-ISOXAZOLYL)AMINO]SULFONYL}-2-THIOPHENECARBOXAMIDE | ENCYSIVE PHARMACEUTICALS, INC. (US) | 2009-06-17 | — | — | EP | claimed |
| US-20060135759-A1 | Reusable universal polymer support for repetitive oligonucleotide synthesis | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH | 2006-06-22 | — | — | US | claimed |
| EP-1436284-B1 | SYNTHESIS OF 4- (Z)-(4-BROMOPHENYL)(ETHOXYIMINO)METHYL]-1'- 2,4-DIMETHYL-1-OXIDO-3-PYRIDINYL)CARBONYL]-4'METHYL-1,4'BIPIPERIDINE | SCHERING CORP (US) | 2005-08-03 | — | — | EP | claimed |
| WO-2005007634-A1 | 3-HYDROXY-4-OXO-1,2,3-TRIAZINES AND DERIVATIVES THEREOF FOR AMIDE AND ESTER BOND FORMATION | FRUTAROM LTD. (IL) | 2005-01-27 | — | — | WO | claimed |
| US-6818773-B2 | AIDS THERAPY; ANTIINFLAMAMTORY AGENTS; ANTIALLERGENS; RHEUMATIC DISEASES | SCHERING CORPORATION | 2004-11-16 | — | — | US | claimed |
| WO-2003033490-A9 | SYNTHESIS OF 4-[(Z)-(4-BROMOPHENYL)(ETHOXYIMINO)METHYL]-1'-[2,4-DIMETHYL-1-OXIDO-3-PYRIDINYL)CARBONYL]-4'METHYL-1,4'BIPIPERIDINE | SCHERING CORP (US) | 2004-06-10 | — | — | WO | claimed |
| US-20040077878-A1 | Process for the preparation of tri-nitrogen containing heteroaryl-diamine derivatives useful as pharmaceutical agents and methods of producing pharmaceutical agents | LIU CHUNJIAN (US) | 2004-04-22 | — | — | US | claimed |
| US-20030105131-A1 | Synthesis of 4-[(Z)-4-bromophenyl)(ethoxyimino) methyl]-1'-[(2,4-dimethyl-1-oxido-3-pyridinyl)carbonyl]-4'-methyl-1,4-'bipiperidine | SCHERING CORPORATION | 2003-06-05 | — | — | US | claimed |
| EP-1091972-A1 | REUSABLE SOLID SUPPORT FOR OLIGONUCLEOTIDE SYNTHESIS | UNIVERSITY TECHNOLOGIES INTERNATIONAL INC. (CA) | 2001-04-18 | — | — | EP | claimed |
| US-6015895-A | REACTING A LINKER COMPOUND WITH A HYDROXY GROUP OF A NUCLEOSIDE AND A SOLID SUPPORT CAPABLE OF ESTERIFICATION; LINKER IS STABILE AGAINST SPONTANEOUS HYDROLYSIS AND EASILY CLEAVED WHEN NECESSARY | UNIVERSITY TECHNOLOGIES INTERNATIONAL INC. (CA) | 2000-01-18 | — | — | US | claimed |
| WO-2000001711-A1 | REUSABLE SOLID SUPPORT FOR OLIGONUCLEOTIDE SYNTHESIS | UNIVERSITY TECHNOLOGIES INTERNATIONAL INC. (CA) | 2000-01-13 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10322104-B2 | Disulfur bridge linkers for conjugation of a cell-binding molecule | CD74, CD2, EPCAM | ALDH1A1 900/4885SMN1; SMN2 3882/4885CYP1A2 4710/4885 |
| US-20240351989-A1 | PROCESS FOR THE PREPARATION OF OLAPARIB, AND CRYSTALLINE FORM THEREOF | PARP1, PARP2, PARP4 | ALDH1A1 1541/4885SMN1; SMN2 3917/4885CYP1A2 590/4885 |
| US-20030105131-A1 | Synthesis of 4-[(Z)-4-bromophenyl)(ethoxyimino) methyl]-1'-[(2,4-dimethyl-1-oxido-3-pyridinyl)carbonyl]-4'-methyl-1,4-'bipiperidine | DNMT1, BCDIN3D, TET1 | ALDH1A1 140/4885SMN1; SMN2 2257/4885CYP1A2 216/4885 |
| US-20040077878-A1 | Process for the preparation of tri-nitrogen containing heteroaryl-diamine derivatives useful as pharmaceutical agents and methods of producing pharmaceutical agents | IMPDH1, IMPDH2, HNMT | ALDH1A1 1115/4885SMN1; SMN2 4681/4885CYP1A2 2020/4885 |
| US-20090318704-A1 | Processes for the Preparation of N-(2-Acetyl-4,6-Dimethylphenyl)-3--2-Thiophenecarboxamide | EDNRB, EDNRA, ECE2 | ALDH1A1 3785/4885SMN1; SMN2 3698/4885CYP1A2 436/4885 |
| US-20060135759-A1 | Reusable universal polymer support for repetitive oligonucleotide synthesis | POLI, PCNA, POLN | ALDH1A1 4169/4885SMN1; SMN2 2305/4885CYP1A2 4762/4885 |
| US-10232051-B2 | Acetylenedicarboxyl linkers and their uses in specific conjugation of a cell-binding molecule | AADAC, EPCAM, DCLRE1A | ALDH1A1 429/4885SMN1; SMN2 4722/4885CYP1A2 3037/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.