SCHEMBL5290069

SCHEMBL5290069

Cc1ccc(OCCOc2ccccc2Cl)cc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 8/20 0.69
MAPT P10636 5/20 0.68
TDP1 Q9NUW8 2/20 0.68
RAB9A P51151 3/20 0.62
HPGD P15428 3/20 0.62
NPC1 O15118 2/20 0.62
CYP2C19 P33261 3/20 0.56
CYP1A2 P05177 2/20 0.56
CYP2C9 P11712 2/20 0.56
CYP3A4 P08684 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
DRD2 P14416 5/20 0.55
DRD4 P21917 5/20 0.55
DRD3 P35462 5/20 0.55
MEN1 O00255 3/20 0.51
KMT2A Q03164 3/20 0.51
CISD1 Q9NZ45 2/20 0.50
ATM Q13315 1/20 0.50
CYP2D6 P10635 1/20 0.49
PPARG P37231 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20005677 0.95 L3MBTL1 (0.71) L3MBTL1MAPTTDP1RAB9AHPGD
SCHEMBL10597748 0.86 L3MBTL1 (0.90) L3MBTL1MAPTTDP1RAB9AHPGD
SCHEMBL9117427 0.86 L3MBTL1 (0.90) L3MBTL1MAPTTDP1RAB9AHPGD
SCHEMBL1592400 0.85 DRD2 (0.72) L3MBTL1MAPTTDP1RAB9AHPGD
SCHEMBL91268 0.83 L3MBTL1 (0.69) L3MBTL1MAPTTDP1RAB9AHPGD
SCHEMBL9808263 0.82 L3MBTL1 (0.68) L3MBTL1MAPTTDP1RAB9AHPGD
SCHEMBL3763522 0.81 DRD2 (0.73) L3MBTL1MAPTTDP1RAB9AHPGD
SCHEMBL78439 0.81 L3MBTL1 (0.63) L3MBTL1MAPTTDP1RAB9AHPGD
SCHEMBL5280785 0.81 L3MBTL1 (0.61) L3MBTL1MAPTTDP1RAB9AHPGD
SCHEMBL5294953 0.80 L3MBTL1 (0.62) L3MBTL1MAPTTDP1RAB9AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006138653-A9 THERMAL RECORDING MATERIALS AND METHODS OF MAKING AND USING THE SAME NASHUA CORP (US) 2007-03-01 WO disclosed
US-20060293181-A1 Thermal recording materials and methods of making and using the same NASHUA CORPORATION 2006-12-28 US disclosed
WO-2006138653-A1 THERMAL RECORDING MATERIALS AND METHODS OF MAKING AND USING THE SAME NASHUA CORPORATION (US) 2006-12-28 WO disclosed
US-RE36321-E INCLUDING DIARYL DIETHER COMPOUND KANSAKI PAPER MANUFACTURING CO., LTD. (JP) 1999-09-28 US disclosed
EP-0141170-B1 HEAT-SENSITIVE RECORDING MATERIAL KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1987-05-13 EP disclosed
US-4659643-A A PHENOXY COMPOUND KANZAKI PAPER MANUFACTURING CO. LTD. (JP) 1987-04-21 US disclosed
US-4531140-A Heat-sensitive recording material Kansaki Paper Manufacturing Co. Ltd. (JP) 1985-07-23 US disclosed
EP-0141170-A2 Heat-sensitive recording material KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1985-05-15 EP disclosed