Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | HTT | P42858 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL529518 | 0.90 | MAPT (0.46) | MAPTHTTALDH1A1NPSR1GAA | |
| SCHEMBL528660 | 0.90 | L3MBTL1 (0.48) | MAPTHTTALDH1A1L3MBTL1HPGD | |
| SCHEMBL528401 | 0.89 | MAPT (0.47) | MAPTHTTALDH1A1NPSR1GAA | |
| SCHEMBL528265 | 0.86 | ALDH1A1 (0.54) | MAPTHTTALDH1A1L3MBTL1HPGD | |
| SCHEMBL529592 | 0.84 | MAPT (0.55) | MAPTALDH1A1NPSR1HPGDSMN1; SMN2 | |
| SCHEMBL528370 | 0.84 | MAPT (0.52) | MAPTHTTALDH1A1NPSR1HPGD | |
| SCHEMBL528858 | 0.82 | ROCK2 (0.51) | MAPTHTTALDH1A1GAAHPGD | |
| SCHEMBL529226 | 0.82 | SMN1; SMN2 (0.48) | MAPTALDH1A1NPSR1SMN1; SMN2NPC1 | |
| SCHEMBL527894 | 0.81 | RXFP1 (0.49) | MAPTHTTALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL528331 | 0.81 | FFAR1 (0.49) | MAPTHTTALDH1A1GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | disclosed |