Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 6/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5286204 | 0.86 | KCNH2 (0.44) | KMT2ALMNARAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL5293214 | 0.82 | HSD17B10 (0.40) | KMT2ALMNARAB9AL3MBTL1MEN1 | |
| SCHEMBL5306349 | 0.74 | ALDH1A1 (0.43) | KMT2AMEN1HSD17B10GAA | |
| SCHEMBL5293205 | 0.74 | TAAR1 (0.43) | KMT2ARAB9AMEN1HSD17B10GAA | |
| SCHEMBL5357947 | 0.73 | ALDH1A1 (0.39) | NPC1KMT2ALMNARAB9ASMN1; SMN2 | |
| SCHEMBL5308656 | 0.70 | MEN1 (0.42) | KMT2ALMNAMEN1KCNH2HSD17B10 | |
| SCHEMBL5301071 | 0.68 | CYP3A4 (0.42) | KMT2ALMNAL3MBTL1MEN1HSD17B10 | |
| SCHEMBL3033576 | 0.64 | KMT2A (0.54) | NPC1KMT2ALMNARAB9ASMN1; SMN2 | |
| SCHEMBL924831 | 0.63 | ALDH1A1 (0.54) | SMN1; SMN2L3MBTL1HSD17B10GAA | |
| SCHEMBL3339186 | 0.62 | NPC1 (0.78) | NPC1KMT2ALMNARAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007012724-A1 | 1,2,4-THIADIAZOLE DERIVATIVES ANTIFUNGAL COMPOUNDS, COMPOSITIONS CONTAINING SAID COMPOUNDS AND THE USE THEREOF | CYTOMICS SYSTEMS (FR) | 2007-02-01 | — | — | WO | claimed |