Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 7/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 5/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | GRM5 | P41594 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5297823 | 0.81 | KMT2A (0.35) | ALDH1A1KDM4EGAAMAPTHPGD | |
| SCHEMBL5299398 | 0.75 | KCNH3 (0.44) | ALDH1A1KDM4EGAAMAPTRAB9A | |
| SCHEMBL5294263 | 0.73 | NPC1 (0.46) | GAARAB9ANPC1KMT2ASMN1; SMN2 | |
| SCHEMBL5288067 | 0.68 | LOX (0.34) | — | |
| SCHEMBL5301119 | 0.66 | LOX (0.30) | — | |
| SCHEMBL12922160 | 0.64 | ALDH1A1 (0.62) | ALDH1A1KDM4EGAAMAPTHPGD | |
| SCHEMBL5368956 | 0.64 | — | — | |
| SCHEMBL5362184 | 0.63 | NPC1 (0.40) | ALDH1A1GAAMAPTHPGDRAB9A | |
| SCHEMBL5362192 | 0.62 | LMNA (0.33) | ALDH1A1MAPTHPGDSMN1; SMN2POLB | |
| SCHEMBL5359842 | 0.62 | LMNA (0.33) | ALDH1A1HPGDSMN1; SMN2POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007012724-A1 | 1,2,4-THIADIAZOLE DERIVATIVES ANTIFUNGAL COMPOUNDS, COMPOSITIONS CONTAINING SAID COMPOUNDS AND THE USE THEREOF | CYTOMICS SYSTEMS (FR) | 2007-02-01 | — | — | WO | disclosed |