Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.40 |
| ▸ | TRAP1 | Q12931 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.39 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | CMA1 | P23946 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5293205 | 0.86 | TAAR1 (0.43) | ALDH1A1HSD17B10TAAR1SLC6A4SLC6A2 | |
| SCHEMBL5293214 | 0.82 | HSD17B10 (0.40) | ALDH1A1HSD17B10TAAR1SLC6A4SLC6A2 | |
| SCHEMBL5308656 | 0.80 | MEN1 (0.42) | ALDH1A1HSD17B10SLC6A4SLC6A2CYP3A4 | |
| SCHEMBL5286204 | 0.78 | KCNH2 (0.44) | ALDH1A1HSD17B10MEN1KMT2AGAA | |
| SCHEMBL5301071 | 0.77 | CYP3A4 (0.42) | ALDH1A1HSD17B10TAAR1SLC6A4SLC6A2 | |
| SCHEMBL5294263 | 0.74 | NPC1 (0.46) | HSD17B10MEN1KMT2AGAA | |
| SCHEMBL5299686 | 0.74 | ADORA3 (0.46) | ALDH1A1HSD17B10CYP2D6 | |
| SCHEMBL30311564 | 0.72 | TAAR1 (0.56) | ALDH1A1HSD17B10TAAR1SLC6A4SLC6A2 | |
| SCHEMBL924831 | 0.72 | ALDH1A1 (0.54) | ALDH1A1HSD17B10TAAR1SLC6A4SLC6A2 | |
| SCHEMBL6528293 | 0.68 | ALDH1A1 (0.52) | ALDH1A1HSD17B10TAAR1SLC6A4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007012724-A1 | 1,2,4-THIADIAZOLE DERIVATIVES ANTIFUNGAL COMPOUNDS, COMPOSITIONS CONTAINING SAID COMPOUNDS AND THE USE THEREOF | CYTOMICS SYSTEMS (FR) | 2007-02-01 | — | — | WO | claimed |
| WO-2007012724-A1 | 1,2,4-THIADIAZOLE DERIVATIVES ANTIFUNGAL COMPOUNDS, COMPOSITIONS CONTAINING SAID COMPOUNDS AND THE USE THEREOF | CYTOMICS SYSTEMS (FR) | 2007-02-01 | — | — | WO | disclosed |