Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SIRT2 | Q8IXJ6 | 7/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | GALR3 | O60755 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RORC | P51449 | 2/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL528483 | 0.91 | MAPT (0.54) | SMN1; SMN2ALDH1A1MEN1KMT2ASIRT2 | |
| SCHEMBL528642 | 0.90 | LMNA (0.48) | SMN1; SMN2SIRT2LMNAPOLBMAPT | |
| SCHEMBL529259 | 0.89 | MAPT (0.55) | SMN1; SMN2ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL528374 | 0.89 | SMN1; SMN2 (0.45) | SMN1; SMN2ALDH1A1MEN1KMT2ASIRT2 | |
| SCHEMBL528511 | 0.87 | KMT2A (0.52) | SMN1; SMN2ALDH1A1MEN1KMT2ASIRT2 | |
| SCHEMBL528823 | 0.87 | MAPT (0.53) | SMN1; SMN2ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL528969 | 0.87 | MAPT (0.60) | SMN1; SMN2ALDH1A1SIRT2LMNAPOLB | |
| SCHEMBL528087 | 0.87 | KMT2A (0.55) | SMN1; SMN2ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL528399 | 0.85 | MAPT (0.56) | SMN1; SMN2ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL528262 | 0.83 | MAPT (0.42) | SMN1; SMN2ALDH1A1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | disclosed |