Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 2/20 | 0.47 |
| ▸ | QPCT | Q16769 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP4Z1 | Q86W10 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.33 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.33 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10770404 | 0.98 | TBXAS1 (0.50) | TBXAS1QPCTCYP3A4CYP2D6CYP1A2 | |
| SCHEMBL28881459 | 0.98 | TBXAS1 (0.50) | TBXAS1QPCTCYP3A4CYP2D6CYP1A2 | |
| Hydrochloric Acid SCHEMBL28469122 | 0.96 | TBXAS1 (0.49) | TBXAS1QPCTCYP3A4CYP2D6CYP1A2 | |
| SCHEMBL28165347 | 0.94 | TBXAS1 (0.44) | TBXAS1QPCTCYP3A4CYP2D6CYP1A2 | |
| SCHEMBL5393991 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL9020707 | 0.84 | QPCT (0.39) | TBXAS1QPCTCYP3A4CYP2D6CYP1A2 | |
| SCHEMBL11883639 | 0.79 | ALDH1A1 (0.40) | CYP2C19ALDH1A1TSHRCYP4Z1POLB | |
| SCHEMBL28030942 | 0.78 | CA12 (0.33) | TBXAS1CYP3A4CYP2D6CYP1A2CYP2C9 | |
| SCHEMBL2786027 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL27744922 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3078738-B1 | WNT PATHWAY STIMULATION IN REPROGRAMMING SOMATIC CELLS | WHITEHEAD INST BIOMEDICAL RES (US) | 2020-05-20 | — | — | EP | claimed |
| EP-2599776-B1 | THERAPEUTIC AGENT FOR NEUROLOGICAL DISEASES | NEUGEN PHARMA INC (JP) | 2014-10-15 | — | — | EP | claimed |
| US-20130190363-A1 | THERAPEUTIC AGENT FOR NEUROLOGICAL DISEASES | WAKUNAGA PHARMACEUTICAL CO., LTD. (JP) | 2013-07-25 | — | — | US | claimed |
| EP-2599776-A1 | THERAPEUTIC AGENT FOR NEUROLOGICAL DISEASES | Neugen Pharma Inc. (JP) | 2013-06-05 | — | — | EP | claimed |
| EP-3078738-B1 | WNT PATHWAY STIMULATION IN REPROGRAMMING SOMATIC CELLS | WHITEHEAD INST BIOMEDICAL RES (US) | 2020-05-20 | — | — | EP | disclosed |
| EP-3601232-A1 | COMPOSITIONS AND METHODS COMPRISING SUBSTITUTED 2-AMINOIMIDAZOLES | Curza Global LLC (US) | 2020-02-05 | — | — | EP | disclosed |
| WO-2018184019-A1 | COMPOSITIONS AND METHODS COMPRISING SUBSTITUTED 2-AMINOIMIDAZOLES | CURZA GLOBAL, LLC (US) | 2018-10-04 | — | — | WO | disclosed |
| EP-3119394-A2 | COMPOSITIONS AND METHODS COMPRISING 2-(ACYLAMINO)IMIDAZOLES | Curza Global LLC (US) | 2017-01-25 | — | — | EP | disclosed |
| CN-105541828-A | Amide imidazole derivative and application thereof | UNIV SHENYANG PHARMACEUTICAL | 2016-05-04 | — | — | CN | disclosed |
| CN-105541828-A | Amide imidazole derivative and application thereof | UNIV SHENYANG PHARMACEUTICAL | 2016-05-04 | — | — | CN | disclosed |
| WO-2015143240-A2 | COMPOSITIONS AND METHODS COMPRISING 2-(ACYLAMINO)IMIDAZOLES | CURZA GLOBAL, LLC (US) | 2015-09-24 | — | — | WO | disclosed |
| US-8975411-B2 | Therapeutic agent for neurological diseases | NEUGEN PHARMA INC. (JP) | 2015-03-10 | — | — | US | disclosed |
| US-20040020568-A1 | Non-toxic corrosion-protection conversion coats based on rare earth elements | DAYTON, UNIVERSITY OF | 2004-02-05 | — | — | US | disclosed |
| US-20040016910-A1 | Non-toxic corrosion-protection rinses and seals based on rare earth elements | DAYTON, UNIVERSITY OF | 2004-01-29 | — | — | US | disclosed |
| US-20040011252-A1 | Non-toxic corrosion-protection pigments based on manganese | UNIVERSITY OF DAYTON | 2004-01-22 | — | — | US | disclosed |
| US-20030234063-A1 | Non-toxic corrosion-protection conversion coats based on cobalt | DAYTON, UNIVERSITY OF | 2003-12-25 | — | — | US | disclosed |
| US-20030230363-A1 | Non-toxic corrosion-protection rinses and seals based on cobalt | UNIVERSITY OF DAYTON | 2003-12-18 | — | — | US | disclosed |
| WO-2003060192-A1 | NON-TOXIC CORROSION-PROTECTION RINSES AND SEALS BASED ON COBALT | UNIVERSITY OF DAYTON (US) | 2003-07-24 | — | — | WO | disclosed |
| WO-2003060191-A2 | NON-TOXIC CORROSION-PROTECTION CONVERSION COATINGES ABSED ON COBALT | UNIVERSITY OF DAYTON (US) | 2003-07-24 | — | — | WO | disclosed |
| WO-2003060019-A1 | NON-TOXIC CORROSION PROTECTION PIGMENTS BASED ON COBALT | UNIVERSITY OF DAYTON (US) | 2003-07-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130190363-A1 | THERAPEUTIC AGENT FOR NEUROLOGICAL DISEASES | AIFM1, AIFM2, GPX4 | TBXAS1 1600/4885QPCT 1917/4885CYP3A4 4358/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.