Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 2/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.34 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5280752 | 0.92 | KMO (0.39) | PDGFRBPDGFRAALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL5281477 | 0.90 | PDGFRB (0.43) | PDGFRBPDGFRAALDH1A1SMN1; SMN2ATM | |
| SCHEMBL5328339 | 0.88 | KIF11 (0.42) | ALDH1A1MAPTHSD17B10 | |
| SCHEMBL5282908 | 0.86 | S1PR1 (0.41) | PDGFRBPDGFRAALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL5298454 | 0.83 | CYP1A2 (0.39) | PDGFRBPDGFRAALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL5285137 | 0.82 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2MAPTLMNAMAPK1 | |
| SCHEMBL4181661 | 0.81 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2MAPTLMNAMAPK1 | |
| SCHEMBL5278083 | 0.80 | ALDH1A1 (0.39) | PDGFRBPDGFRACHRNA7ALDH1A1SMN1; SMN2 | |
| SCHEMBL5276956 | 0.79 | MAPT (0.42) | ALDH1A1SMN1; SMN2MAPTLMNANPC1 | |
| SCHEMBL5280707 | 0.79 | KMT2A (0.40) | ALDH1A1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1866289-A1 | PYRIMIDINE CARBOXYLIC ACID DERIVATIVES AND USE THEREOF | Bayer HealthCare AG (DE) | 2007-12-19 | — | — | EP | disclosed |
| WO-2006097220-A1 | PYRIMIDINE CARBOXYLIC ACID DERIVATIVES AND USE THEREOF | BAYER HEALTHCARE AG (DE) | 2006-09-21 | — | — | WO | disclosed |