Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | XPO1 | O14980 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.36 |
| ▸ | ATF1 | P18846 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | FOS | P01100 | 1/20 | 0.36 |
| ▸ | JUN | P05412 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5328339 | 0.81 | KIF11 (0.42) | KMT2AMEN1MAPTKDM4EHSP90AA1 | |
| SCHEMBL5126930 | 0.81 | KDM4E (0.49) | KMT2AMEN1MAPTKDM4EHSP90AA1 | |
| SCHEMBL5285137 | 0.79 | ALDH1A1 (0.54) | KMT2AMEN1MAPTKDM4EGAA | |
| SCHEMBL5299485 | 0.79 | PDGFRB (0.38) | MAPTGAAALDH1A1 | |
| SCHEMBL5282908 | 0.79 | S1PR1 (0.41) | KMT2AMAPTKDM4EGAAPOLB | |
| SCHEMBL5280752 | 0.78 | KMO (0.39) | MAPTKDM4EALDH1A1 | |
| SCHEMBL5281477 | 0.76 | PDGFRB (0.43) | KMT2AMEN1KDM4EGAAALDH1A1 | |
| SCHEMBL5298454 | 0.76 | CYP1A2 (0.39) | MAPTKDM4EPOLBALDH1A1 | |
| SCHEMBL5118532 | 0.73 | ALDH1A1 (0.55) | MAPTKDM4EXPO1POLBALDH1A1 | |
| SCHEMBL5276956 | 0.73 | MAPT (0.42) | KMT2AMEN1MAPTKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1866289-A1 | PYRIMIDINE CARBOXYLIC ACID DERIVATIVES AND USE THEREOF | Bayer HealthCare AG (DE) | 2007-12-19 | — | — | EP | disclosed |
| WO-2006097220-A1 | PYRIMIDINE CARBOXYLIC ACID DERIVATIVES AND USE THEREOF | BAYER HEALTHCARE AG (DE) | 2006-09-21 | — | — | WO | disclosed |