Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | MB | P02144 | 1/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3030037 | 0.88 | LMNA (0.60) | LMNAALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL9525976 | 0.83 | LMNA (0.52) | LMNAALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL10620132 | 0.82 | LMNA (0.54) | LMNAALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL10394559 | 0.78 | ENPP2 (0.48) | LMNAALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL5305674 | 0.77 | LMNA (0.48) | LMNAALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL2081736 | 0.77 | TDP1 (0.57) | ALDH1A1TDP1MEN1KMT2AHSD17B10 | |
| SCHEMBL30483162 | 0.77 | TDP1 (0.57) | ALDH1A1TDP1MEN1KMT2AHSD17B10 | |
| SCHEMBL10925247 | 0.77 | SMN1; SMN2 (0.51) | LMNAALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL1832506 | 0.77 | ALDH1A1 (0.57) | ALDH1A1TDP1MEN1KMT2AHSD17B10 | |
| SCHEMBL2933889 | 0.76 | HTT (0.56) | LMNAALDH1A1TDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007034282-A2 | DIARYL-IMIDAZOLE COMPOUNDS CONDENSED WITH A HETEROCYCLE AS C3A RECEPTOR ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2007-03-29 | — | — | WO | disclosed |