Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | MB | P02144 | 1/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.42 |
| ▸ | CA3 | P07451 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5300918 | 0.83 | LMNA (0.48) | LMNAPKMALDH1A1TDP1GAA | |
| SCHEMBL10394559 | 0.76 | ENPP2 (0.48) | LMNAPKMALDH1A1TDP1GAA | |
| SCHEMBL24728205 | 0.76 | LMNA (0.64) | LMNAPKMALDH1A1TDP1GAA | |
| SCHEMBL33701 | 0.76 | PKM (0.59) | LMNAPKMALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL29415477 | 0.76 | PKM (0.59) | LMNAPKMALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL4055616 | 0.76 | TDP1 (0.57) | LMNAPKMALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL2933889 | 0.75 | HTT (0.56) | LMNAPKMALDH1A1TDP1GAA | |
| Hydrochloric Acid SCHEMBL7155376 | 0.74 | PKM (0.57) | LMNAPKMALDH1A1TDP1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11740154 | 0.74 | TDP1 (0.55) | LMNAPKMALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL11037405 | 0.74 | CA2 (0.49) | LMNAPKMALDH1A1TDP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0366542-B1 | 5-SUBSTITUTED ORTHO-AMINOPHENOLS, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THE OXIDATION DYEING OF KERATINIC FIBRES | L'OREAL (FR) | 1993-07-14 | — | — | EP | disclosed |
| EP-0366542-A1 | 5-Substituted ortho-aminophenols, process for their preparation and their use in the oxidation dyeing of keratinic fibres | L'OREAL (FR) | 1990-05-02 | — | — | EP | disclosed |