Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.40 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.40 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | MME | P08473 | 2/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | CPA1 | P15085 | 1/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10435634 | 0.82 | PRKCZ (0.44) | KMT2APTGER1PTGER3PTGER2ACACB | |
| Maleic Acid SCHEMBL9879499 | 0.80 | ADRA2C (0.49) | KMT2APTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL10435703 | 0.78 | ALDH1A1 (0.47) | KMT2AMMEACECPA1ACE2 | |
| Hydrochloric Acid SCHEMBL11508056 | 0.77 | ADRB2 (0.48) | KMT2AACACBALDH1A1NPC1RAB9A | |
| SCHEMBL3787571 | 0.70 | DPP4 (0.64) | KMT2APTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL14345777 | 0.70 | NPC1 (0.69) | KMT2AACACBALDH1A1L3MBTL1NPC1 | |
| SCHEMBL3787028 | 0.69 | MAOA (0.50) | KMT2APTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL19966634 | 0.66 | KDM4E (0.60) | KMT2AACEKDM4EALDH1A1MAPT | |
| SCHEMBL25470419 | 0.66 | KCNA5 (0.51) | CHRM3KDM4EALDH1A1MAPTL3MBTL1 | |
| SCHEMBL19960931 | 0.65 | CTSC (0.55) | ACENPC1RAB9AAOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007017652-A2 | ARYLAKYLAMINES FOR THE TREATMENT OF CANCER | ASTRAZENECA AB (SE) | 2007-02-15 | — | — | WO | claimed |