Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | MPO | P05164 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | KDM5A | P29375 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | OGG1 | O15527 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | PTAFR | P25105 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5487653 | 0.85 | NR1H4 (0.56) | MAPK14MAPTMPOCYP3A4KDM5A | |
| SCHEMBL752600 | 0.82 | MPO (0.70) | MAPTMPOCYP3A4KDM5ABLM | |
| SCHEMBL14238637 | 0.81 | ALDH1A1 (0.60) | MAPTMPOCYP3A4KDM5ABLM | |
| SCHEMBL17044693 | 0.81 | MPO (0.61) | MAPK14MAPTMPOCYP3A4KDM5A | |
| SCHEMBL31547637 | 0.79 | BRD4 (0.58) | CA1CA2MCL1CA9 | |
| SCHEMBL5304379 | 0.77 | KMT2A (0.45) | MAPTL3MBTL1LMNAPTAFRKMT2A | |
| SCHEMBL10304773 | 0.77 | HSD17B1 (0.57) | MAPTL3MBTL1LMNAKMT2ANPC1 | |
| SCHEMBL3234816 | 0.77 | RXRA (0.62) | KDM4EALDH1A1LMNAMCL1NR1H4 | |
| SCHEMBL23067282 | 0.76 | BLM (0.57) | MAPTMPOCYP3A4KDM5ABLM | |
| SCHEMBL13830583 | 0.76 | TDP1 (0.57) | MAPTCA1CA2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007034282-A2 | DIARYL-IMIDAZOLE COMPOUNDS CONDENSED WITH A HETEROCYCLE AS C3A RECEPTOR ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2007-03-29 | — | — | WO | disclosed |