Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.54 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | MPO | P05164 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | KDM5A | P29375 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2810590 | 0.86 | MAPT (0.50) | NR1H4MPOCYP3A4KDM5ABLM | |
| SCHEMBL22441042 | 0.86 | MYC (0.55) | MPOCYP3A4KDM5ABLMGFER | |
| SCHEMBL5301581 | 0.85 | MAPK14 (0.54) | NR1H4KMT2AMEN1MPOCYP3A4 | |
| SCHEMBL1628213 | 0.84 | ALDH1A1 (0.57) | MPOCYP3A4KDM5ABLMGFER | |
| SCHEMBL4809042 | 0.84 | MAPT (0.66) | MPOCYP3A4KDM5ABLMGFER | |
| SCHEMBL9646049 | 0.82 | MYC (0.53) | KMT2AMEN1MPOCYP3A4KDM5A | |
| SCHEMBL15006963 | 0.82 | HDAC1 (0.51) | MPOCYP3A4KDM5ABLMGFER | |
| SCHEMBL1459893 | 0.82 | OGG1 (0.55) | MPOCYP3A4KDM5ABLMGFER | |
| SCHEMBL18423953 | 0.82 | HDAC1 (0.71) | KMT2AMPOCYP3A4KDM5ABLM | |
| SCHEMBL29225419 | 0.82 | ALDH1A1 (0.55) | KMT2AMEN1MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119977832-A | Benzoyl hydrazine antineoplastic compound and preparation method and application thereof | 江苏海洋大学 | 2025-05-13 | — | — | CN | claimed |
| CN-119977832-A | Benzoyl hydrazine antineoplastic compound and preparation method and application thereof | 江苏海洋大学 | 2025-05-13 | — | — | CN | disclosed |
| WO-2023073115-A1 | PROTEIN AGGREGATION INHIBITING COMPOUNDS FOR PLANT DISEASE CONTROL | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2023-05-04 | — | — | WO | disclosed |
| US-11634391-B2 | Compounds which are inhibitors of Notum | UCL BUSINESS LTD (GB) | 2023-04-25 | — | — | US | disclosed |
| CN-114230517-A | Method for processing eltrombopag | 杭州煌森生物科技有限公司 | 2022-03-25 | — | — | CN | disclosed |
| EP-3843844-A1 | COMPOUNDS | UCL Business Ltd (GB) | 2021-07-07 | — | — | EP | disclosed |
| CN-113024465-A | Preparation method of stable-performance eltrombopag | 杭州煌森生物科技有限公司 | 2021-06-25 | — | — | CN | disclosed |
| US-20210171475-A1 | COMPOUNDS | UCL BUSINESS LTD (GB) | 2021-06-10 | — | — | US | disclosed |
| WO-2020043866-A1 | COMPOUNDS | UCL BUSINESS LTD (GB) | 2020-03-05 | — | — | WO | disclosed |
| US-20170253569-A1 | THIAZOLIDINONE COMPOUNDS AND USE THEREOF | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2017-09-07 | — | — | US | disclosed |
| EP-1819341-A2 | IL-12 MODULATORY COMPOUNDS | Synta Pharmaceuticals Corporation (US) | 2007-08-22 | — | — | EP | disclosed |
| US-7166623-B2 | 2′-Methyl-5′-(1,3,4-oxadiazol-2-yl)-1,1′-biphenyl-4-carboxamide derivatives and their use as p38 kinase inhibitors | GLAXO GROUP LIMITED (GB) | 2007-01-23 | — | — | US | disclosed |
| US-7166623-B2 | 2′-Methyl-5′-(1,3,4-oxadiazol-2-yl)-1,1′-biphenyl-4-carboxamide derivatives and their use as p38 kinase inhibitors | GLAXO GROUP LIMITED (GB) | 2007-01-23 | — | — | US | disclosed |
| WO-2006053227-A2 | IL-12 MODULATORY COMPOUNDS | SYNTA PHARMACEUTICALS CORP. (US) | 2006-05-18 | — | — | WO | disclosed |
| EP-0088729-B1 | USE OF METAL COMPLEXES OF HYDRAZONES AS PIGMENTS | CIBA-GEIGY AG (CH) | 1987-07-29 | — | — | EP | disclosed |
| US-4612014-A | Use of metal complexes of hydrazones as pigments | CIBA-GEIGY CORPORATION (US) | 1986-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11634391-B2 | Compounds which are inhibitors of Notum | NOTUM, GOT2, GOT1 | NR1H4 257/4885KMT2A 4180/4885TAS1R3 4367/4885 |
| US-20210171475-A1 | COMPOUNDS | GOT2, GOT1, OAT | NR1H4 68/4885KMT2A 3672/4885TAS1R3 4049/4885 |
| US-20170253569-A1 | THIAZOLIDINONE COMPOUNDS AND USE THEREOF | OPRL1, OPRD1, OPRK1 | NR1H4 7/4885KMT2A 3536/4885TAS1R3 932/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.