Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GBA1 | P04062 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7221265 | 0.83 | KMT2A (0.58) | ALDH1A1HTTTDP1KDM4ERAB9A | |
| SCHEMBL27964357 | 0.82 | ALDH1A1 (0.53) | ALDH1A1HTTTDP1KDM4ERAB9A | |
| SCHEMBL6561226 | 0.82 | ALDH1A1 (0.53) | ALDH1A1HTTTDP1KDM4ERAB9A | |
| SCHEMBL15331980 | 0.80 | ALDH5A1 (0.48) | ALDH1A1HTTLMNAKMT2AMEN1 | |
| SCHEMBL8846996 | 0.79 | KMT2A (0.47) | ALDH1A1HTTTDP1KDM4ERAB9A | |
| SCHEMBL11404976 | 0.79 | ALDH1A1 (0.43) | ALDH1A1HTTTDP1KDM4ERAB9A | |
| SCHEMBL2555020 | 0.79 | ALDH5A1 (0.47) | ALDH1A1HTTPOLBLMNAKMT2A | |
| SCHEMBL8036807 | 0.79 | CRHBP (0.53) | ALDH1A1KDM4EPOLBLMNAKMT2A | |
| SCHEMBL4824448 | 0.78 | L3MBTL1 (0.62) | ALDH1A1HTTTDP1KDM4ERAB9A | |
| SCHEMBL3043522 | 0.78 | ALDH1A1 (0.59) | ALDH1A1HTTTDP1KDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2598522-A2 | RECOMBINANT LECTINS, BINDING-SITE MODIFIED LECTINS AND USES THEREOF | Smartcells, Inc. (US) | 2013-06-05 | — | — | EP | disclosed |
| WO-2012015691-A2 | RECOMBINANT LECTINS, BINDING-SITE MODIFIED LECTINS AND USES THEREOF | SMARTCELLS, INC. (US) | 2012-02-02 | — | — | WO | disclosed |
| EP-2331017-A1 | ESOPHAGEAL VALVE | VYS RA Biomedical Limited (IE) | 2011-06-15 | — | — | EP | disclosed |
| WO-2009153768-A1 | ESOPHAGEAL VALVE | VYSΕRA BIOMEDICAL LIMITED (IE) | 2009-12-23 | — | — | WO | disclosed |