Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 5/20 | 0.40 |
| ▸ | CA2 | P00918 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 2/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.39 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13203916 | 0.74 | ATM (0.43) | CES2CES1CA1CA2MAPT | |
| SCHEMBL27915450 | 0.71 | CYP3A4 (0.43) | CES2CES1CA1CA2MAPT | |
| SCHEMBL5287713 | 0.71 | HSD11B1 (0.51) | CES2CES1CA1CA2MAPT | |
| SCHEMBL5298336 | 0.70 | CA1 (0.48) | CA1CA2MAPTRAB9AMAPK1 | |
| SCHEMBL10765712 | 0.68 | CA1 (0.46) | CA1CA2MAPTRAB9AMAPK1 | |
| SCHEMBL11823191 | 0.68 | KCNA3 (0.44) | CES2CES1CA1CA2MAPT | |
| 1,4-Dimethoxybenzene SCHEMBL28051166 | 0.68 | CA1 (0.68) | CES2CES1CA1CA2MAPT | |
| SCHEMBL1871227 | 0.66 | LMNA (0.67) | CES2CES1CA1CA2MAPT | |
| SCHEMBL155983 | 0.66 | LMNA (0.67) | CES2CES1CA1CA2MAPT | |
| SCHEMBL4593299 | 0.66 | ALDH1A1 (0.46) | CA1CA2MAPTMAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007001335-A2 | RAMOPLANIN DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | VICURON PHARMACEUTICALS INC. (US) | 2007-01-04 | — | — | WO | disclosed |