Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | LDHA | P00338 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | CES2 | O00748 | 2/20 | 0.40 |
| ▸ | CES1 | P23141 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5291028 | 0.78 | PKM (0.47) | HSD11B1CA1CA2MAPTRAB9A | |
| SCHEMBL5301951 | 0.71 | CES2 (0.41) | CA1CA2PDE4BNPSR1MAPT | |
| SCHEMBL364190 | 0.71 | HSD11B1 (0.65) | HSD11B1KMT2AALDH1A1HPGD | |
| SCHEMBL28472946 | 0.69 | CA1 (0.50) | HSD11B1CA1CA2LDHAMAPT | |
| SCHEMBL4593299 | 0.68 | ALDH1A1 (0.46) | CA1CA2MAPTMAPK1KMT2A | |
| SCHEMBL13216336 | 0.68 | HSD11B1 (1.00) | HSD11B1KMT2A | |
| SCHEMBL10765712 | 0.67 | CA1 (0.46) | CA1CA2NPSR1MAPTRAB9A | |
| 1,4-Dimethoxybenzene SCHEMBL28051166 | 0.66 | CA1 (0.68) | CA1CA2LDHAMAPTCES2 | |
| SCHEMBL19438755 | 0.66 | KMT2A (0.54) | HSD11B1CA1CA2MAPTCES2 | |
| SCHEMBL656832 | 0.65 | LMNA (0.67) | MAPTKMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007001335-A2 | RAMOPLANIN DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | VICURON PHARMACEUTICALS INC. (US) | 2007-01-04 | — | — | WO | disclosed |