Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 2/20 | 0.69 |
| ▸ | PDCD1 | Q15116 | 3/20 | 0.50 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.50 |
| ▸ | HNF4A | P41235 | 1/20 | 0.50 |
| ▸ | MYC | P01106 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | IKBKB | O14920 | 2/20 | 0.45 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30034930 | 1.00 | BCAT2 (0.69) | BCAT2PDCD1CD274HNF4AMYC | |
| SCHEMBL6307908 | 0.93 | BCAT2 (0.65) | BCAT2PDCD1CD274HNF4AMYC | |
| Trifluoroacetic Acid SCHEMBL1785126 | 0.91 | BCAT2 (0.57) | BCAT2PDCD1CD274HNF4AMYC | |
| SCHEMBL30471810 | 0.86 | BCAT2 (0.52) | BCAT2MYCBRD4KEAP1NFE2L2 | |
| SCHEMBL29941849 | 0.86 | MKNK1 (0.55) | BCAT2PDCD1CD274KEAP1NFE2L2 | |
| SCHEMBL7311563 | 0.85 | BCAT2 (0.58) | BCAT2PDCD1CD274BRD4NPC1 | |
| SCHEMBL3898825 | 0.85 | BCAT2 (0.58) | BCAT2PDCD1CD274MEN1KMT2A | |
| SCHEMBL121422 | 0.85 | HNF4A (0.63) | BCAT2PDCD1CD274HNF4AMYC | |
| SCHEMBL17803632 | 0.84 | SLC6A4 (0.51) | BCAT2MEN1KMT2AKEAP1NFE2L2 | |
| SCHEMBL13065950 | 0.83 | PDCD1 (0.52) | BCAT2PDCD1CD274HNF4AMYC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108883122-A | C-glycoside compounds useful for the treatment of diseases | 菲姆布里昂医疗公司 | 2018-11-23 | — | — | CN | claimed |
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | claimed |
| CN-101448792-A | Compounds that potentiate AMPA receptors and their use in medicine | GLAXO GROUP LTD (GB) | 2009-06-03 | — | — | CN | claimed |
| CN-116041277-A | Phenyl and biphenyl substituted five-membered heterocyclic compound, preparation method, pharmaceutical composition and application thereof | 中国药科大学 | 2023-05-02 | — | — | CN | disclosed |
| US-10736829-B2 | Use of certain hydroxybenzoic acid amides for masking unpleasant taste impressions | SYMRISE AG (DE) | 2020-08-11 | — | — | US | disclosed |
| CN-105164142-B | Mannose Derivatives for the Treatment of Bacterial Infections | 沃泰克斯药物股份有限公司 | 2019-03-08 | — | — | CN | disclosed |
| CN-108883122-A | C-glycoside compounds useful for the treatment of diseases | 菲姆布里昂医疗公司 | 2018-11-23 | — | — | CN | disclosed |
| US-20180311132-A1 | USE OF CERTAIN HYDROXYBENZOIC ACID AMIDES FOR MASKING UNPLEASANT TASTE IMPRESSIONS | SYMRISE AG (DE) | 2018-11-01 | — | — | US | disclosed |
| CN-104804048-B | N substituted benzyl amino phosphine clamp ring ruthenium diphosphine compounds and its preparation method and application | 洛阳师范学院 | 2017-09-22 | — | — | CN | disclosed |
| US-9458110-B2 | Phenylpyrazole derivatives as potent ROCK1 and ROCK2 inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2016-10-04 | — | — | US | disclosed |
| US-20160016910-A1 | PHENYLPYRAZOLE DERIVATIVES AS POTENT ROCK1 AND ROCK2 INHIBITORS | BRISTOL-MEYERS SQUIBB COMPANY (US) | 2016-01-21 | — | — | US | disclosed |
| WO-2002012210-A1 | BIPHENYL DERIVATIVES AND THEIR USE AS PPAR-GAMMA RECEPTOR ACTIVATORS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2002-02-14 | — | — | WO | disclosed |
| CN-1284957-A | Imidazonaphthyridines and their use in inducing cytokine biosynthesis | MINNESOTA MINING & MFG (US) | 2001-02-21 | — | — | CN | disclosed |
| US-5889001-A | TREATING CONDITIONS WHERE DECREASED VASOPRESSIN LEVELS ARE DESIRED AND DISEASES WITH EXCESS RENAL WATER REABSORPTION | AMERICAN CYANAMID COMPANY (US) | 1999-03-30 | — | — | US | disclosed |
| US-5854237-A | Tricyclic diazepine vasopressin antagonists and oxytocin antagonists | AMERICAN CYANAMID COMPANY (US) | 1998-12-29 | — | — | US | disclosed |
| US-5843944-A | Tricyclic diazepine vasopressin antagonists and oxytocin antagonists | AMERICAN CYANAMID COMPANY (US) | 1998-12-01 | — | — | US | disclosed |
| US-5736540-A | CONGESTIVE HEART FAILURE | AMERICAN CYANAMID COMPANY (US) | 1998-04-07 | — | — | US | disclosed |
| US-5733905-A | CONGESTIVE HEART FAILURE; KIDNEY DISORDERS | AMERICAN CYANAMID COMPANY (US) | 1998-03-31 | — | — | US | disclosed |
| CN-1166832-A | Substituted biphenyl oxazolines | BAYER AG (DE) | 1997-12-03 | — | — | CN | disclosed |
| WO-1996022295-A9 | TRICYCLIC BENZAZEPINE VASOPRESSIN ANTAGONISTS | — | 1996-11-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10736829-B2 | Use of certain hydroxybenzoic acid amides for masking unpleasant taste impressions | FAM222B, FAM83B, CDY1; CDY1B | BCAT2 54/4885PDCD1 2090/4885CD274 2187/4885 |
| US-20180311132-A1 | USE OF CERTAIN HYDROXYBENZOIC ACID AMIDES FOR MASKING UNPLEASANT TASTE IMPRESSIONS | FAM222B, FAM83B, CDY1; CDY1B | BCAT2 54/4885PDCD1 2090/4885CD274 2187/4885 |
| US-20160016910-A1 | PHENYLPYRAZOLE DERIVATIVES AS POTENT ROCK1 AND ROCK2 INHIBITORS | ROCK1, ROCK2, MYLK | BCAT2 3341/4885PDCD1 495/4885CD274 1082/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.