Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.94 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.94 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.94 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.94 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.94 |
| ▸ | MAOA | P21397 | 3/20 | 0.64 |
| ▸ | MAOB | P27338 | 3/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | HTR6 | P50406 | 2/20 | 0.56 |
| ▸ | HTR2C | P28335 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenethylamine SCHEMBL31461079 | 0.97 | HTR2A (0.89) | HTR2ALOXL2TAAR1CYP2A6SMN1; SMN2 | |
| Phenethylamine SCHEMBL11664723 | 0.97 | HTR2A (0.89) | HTR2ALOXL2TAAR1CYP2A6SMN1; SMN2 | |
| Phenethylamine SCHEMBL27634208 | 0.97 | HTR2A (1.00) | HTR2ALOXL2TAAR1CYP2A6SMN1; SMN2 | |
| Phenethylamine SCHEMBL1330939 | 0.97 | — | — | |
| Phenethylamine SCHEMBL968 | 0.97 | — | — | |
| Phenethylamine SCHEMBL1332244 | 0.97 | — | — | |
| Phenethylamine SCHEMBL1331271 | 0.97 | — | — | |
| Phenethylamine SCHEMBL1799333 | 0.97 | HTR2A (1.00) | HTR2ALOXL2TAAR1CYP2A6SMN1; SMN2 | |
| Phenethylamine SCHEMBL8384113 | 0.94 | HTR2A (0.94) | HTR2ALOXL2TAAR1CYP2A6SMN1; SMN2 | |
| Phenethylamine SCHEMBL245154 | 0.94 | HTR2A (0.94) | HTR2ALOXL2TAAR1CYP2A6SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102627571-A | Preparation and synthesis method for chiral ammonium salt | MEI LUO | 2012-08-08 | — | — | CN | claimed |
| CN-113423436-B | Microbiota metabolites that shape host physiology | 耶鲁大学 | 2024-02-06 | — | — | CN | disclosed |
| CN-113437222-B | Lead-free tin-based perovskite thin film, lead-free tin-based perovskite solar cell and preparation method thereof | 西北工业大学 | 2023-09-08 | — | — | CN | disclosed |
| US-20230043198-A1 | MICROBIOTA METABOLITES THAT SHAPE HOST PHYSIOLOGY | YALE UNIVERSITY (US) | 2023-02-09 | — | — | US | disclosed |
| EP-3893941-A1 | MICROBIOTA METABOLITES THAT SHAPE HOST PHYSIOLOGY | Yale University (US) | 2021-10-20 | — | — | EP | disclosed |
| CN-113437222-A | Lead-free tin-based perovskite thin film, lead-free tin-based perovskite solar cell and preparation method of lead-free tin-based perovskite solar cell | 西北工业大学 | 2021-09-24 | — | — | CN | disclosed |
| CN-113423436-A | Metabolites of microbial populations that shape host physiology | 耶鲁大学 | 2021-09-21 | — | — | CN | disclosed |
| WO-2020123376-A1 | MICROBIOTA METABOLITES THAT SHAPE HOST PHYSIOLOGY | YALE UNIVERSITY (US) | 2020-06-18 | — | — | WO | disclosed |
| WO-2020063216-A1 | PEPTOID COMPOUND AND PREPARATION METHOD THEREFOR, OLIGOMER, PHARMACEUTICAL COMPOSITION AND KIT | 京东方科技集团股份有限公司 | 2020-04-02 | — | — | WO | disclosed |
| US-20190298661-A1 | Transdermal Delivery of Phenethylamine Monoamine Releasers | THE CORPORATION OF MERCER UNIVERSITY | 2019-10-03 | — | — | US | disclosed |
| US-6762052-B1 | THE ENZYMES ARE USEFUL IN METABOLISM STUDIES, IN SCREENING OF COMPOUNDS FOR BIOLOGICAL OR PHARMACOLOGICAL ACTIVITY, AS WELL AS SERVING AS A BIO-INDICATOR OF DISEASE STATES OR SUSCEPTIBILITY TO DISEASE STATES | CASHMAN JOHN R | 2004-07-13 | — | — | US | disclosed |
| EP-1076649-A1 | ISOQUINOLINE COMPOUND MELANOCORTIN RECEPTOR LIGANDS AND METHODS OF USING SAME | TREGA BIOSCIENCES, INC. (US) | 2001-02-21 | — | — | EP | disclosed |
| US-6127381-A | A MELANOCORTIN RECEPTOR LIGAND FOR REGULATING FOOD INTAKE AND BODY WEIGHT, REGULATING CYTOKINE ACTIVITY, ANTI-INFLAMMATORY ACTIVITY | LION BIOSCIENCE AG (DE) | 2000-10-03 | — | — | US | disclosed |
| WO-1999055679-A1 | ISOQUINOLINE COMPOUND MELANOCORTIN RECEPTOR LIGANDS AND METHODS OF USING SAME | TREGA BIOSCIENCES, INC. (US) | 1999-11-04 | — | — | WO | disclosed |
| EP-0434213-B1 | Monosubstituted dithiooxamide compounds and their use | MINNESOTA MINING & MFG (US) | 1995-04-05 | — | — | EP | disclosed |
| US-5124308-A | Reacts with transition metal salt for carbonless paper copying | MINNESOTA MINING AND MANUFACTURING COMPANY | 1992-06-23 | — | — | US | disclosed |
| US-5041654-A | Transamination in wallach reaction; controlling temperature; reactant amine concentration | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1991-08-20 | — | — | US | disclosed |
| EP-0434213-A1 | Monosubstituted dithiooxamide compounds and their use | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1991-06-26 | — | — | EP | disclosed |
| EP-0431783-A1 | Preparation of monosubstituted dithiooxamide compounds | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1991-06-12 | — | — | EP | disclosed |
| US-4280958-A | COPPER-TYPE CATALYST USED IN CYCLIZATION OF A HALOGENOPHENETHYLAMINE IN THE PRESENCE OF AN AMINE | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 1981-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190298661-A1 | Transdermal Delivery of Phenethylamine Monoamine Releasers | PNMT, TAAR5, QDPR | HTR2A 62/4885LOXL2 4453/4885TAAR1 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.