Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 19/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4896218 | 1.00 | DNM1 (0.73) | DNM1 | |
| SCHEMBL21887619 | 0.88 | LMNA (0.60) | DNM1 | |
| SCHEMBL410770 | 0.84 | DNM1 (1.00) | DNM1 | |
| SCHEMBL410011 | 0.82 | DNM1 (0.72) | DNM1 | |
| SCHEMBL28590221 | 0.79 | ALDH1A1 (0.58) | DNM1 | |
| SCHEMBL16604024 | 0.79 | RAD52 (0.74) | DNM1 | |
| SCHEMBL28604202 | 0.77 | ALDH1A1 (0.56) | DNM1 | |
| SCHEMBL28583934 | 0.77 | ALDH1A1 (0.56) | DNM1 | |
| SCHEMBL21093338 | 0.77 | ALDH1A1 (0.56) | DNM1 | |
| SCHEMBL30645234 | 0.77 | ALDH1A1 (0.56) | DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070148185-A1 | Novel therapeutic target for protozoal diseases | VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY | 2007-06-28 | — | — | US | claimed |
| WO-2007047579-A2 | A NOVEL THERAPEUTIC TARGET FOR PROTOZOAL DISEASES | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 2007-04-26 | — | — | WO | claimed |