SCHEMBL4896218

SCHEMBL4896218

OC(CNCc1ccccc1)Cn1c2ccc(Cl)cc2c2cc(Cl)ccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 19/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5307308 1.00 DNM1 (0.73) DNM1
SCHEMBL21887619 0.88 LMNA (0.60) DNM1
SCHEMBL410770 0.84 DNM1 (1.00) DNM1
SCHEMBL410011 0.82 DNM1 (0.72) DNM1
SCHEMBL28590221 0.79 ALDH1A1 (0.58) DNM1
SCHEMBL16604024 0.79 RAD52 (0.74) DNM1
SCHEMBL28604202 0.77 ALDH1A1 (0.56) DNM1
SCHEMBL28583934 0.77 ALDH1A1 (0.56) DNM1
SCHEMBL21093338 0.77 ALDH1A1 (0.56) DNM1
SCHEMBL30645234 0.77 ALDH1A1 (0.56) DNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106518750-B Carbazole amino alcohol compound, preparation method thereof and application of carbazole amino alcohol compound in resisting parasitic diseases 中国疾病预防控制中心寄生虫病预防控制所 2021-06-01 CN claimed
CN-106518750-B Carbazole amino alcohol compound, preparation method thereof and application of carbazole amino alcohol compound in resisting parasitic diseases 中国疾病预防控制中心寄生虫病预防控制所 2021-06-01 CN disclosed
US-20080027044-A1 Prodrug antibiotic screens NORTHEASTERN UNIVERSITY 2008-01-31 US disclosed
US-20080027044-A1 Prodrug antibiotic screens NORTHEASTERN UNIVERSITY 2008-01-31 US disclosed
US-20080027044-A1 Prodrug antibiotic screens NORTHEASTERN UNIVERSITY 2008-01-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080027044-A1 Prodrug antibiotic screens O60361, PGLS, GUSB DNM1 3145/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.