Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.41 |
| ▸ | SCD | O00767 | 3/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 2/20 | 0.39 |
| ▸ | PTGES | O14684 | 4/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.38 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.38 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.38 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.38 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.38 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.38 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5307816 | 0.96 | HCRTR1 (0.43) | DPP4DPP7SCDHCRTR1MAPK14 | |
| SCHEMBL5311601 | 0.96 | PTGES (0.44) | DPP4DPP7SCDHCRTR1PTGES | |
| SCHEMBL5308057 | 0.95 | PTGES (0.45) | SCDHCRTR1PTGESALDH1A1L3MBTL1 | |
| SCHEMBL5309106 | 0.87 | HPGD (0.41) | SCDDHODHFLT3PRKAB2PRKAG1 | |
| SCHEMBL5313055 | 0.86 | KDM4E (0.52) | SCDHCRTR1DHODHL3MBTL1MGLL | |
| SCHEMBL5307867 | 0.84 | ABL1 (0.41) | SCDHCRTR1PTGESFLT3L3MBTL1 | |
| SCHEMBL5312923 | 0.83 | NPC1 (0.44) | ALDH1A1L3MBTL1 | |
| SCHEMBL5313034 | 0.80 | MGLL (0.45) | SCDMAPK14ALDH1A1L3MBTL1MGLL | |
| SCHEMBL5307724 | 0.78 | USP30 (0.47) | DPP4DPP7SCDHCRTR1PTGES | |
| SCHEMBL5329482 | 0.74 | KDM4E (0.48) | SCDDHODHL3MBTL1MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007044085-A2 | HETEROARYL COMPOUNDS AND THEIR USES AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2007-04-19 | — | — | WO | disclosed |