Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 9/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SCD | O00767 | 1/20 | 0.40 |
| ▸ | F2R | P25116 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5308057 | 0.99 | PTGES (0.45) | PTGESHCRTR1CNR1KDM4EGLA | |
| SCHEMBL5307816 | 0.98 | HCRTR1 (0.43) | PTGESHCRTR1CNR1SCDDPP4 | |
| SCHEMBL5307458 | 0.96 | DPP4 (0.41) | PTGESHCRTR1L3MBTL1SCDDPP4 | |
| SCHEMBL5307867 | 0.86 | ABL1 (0.41) | PTGESHCRTR1KDM4EGLAHTT | |
| SCHEMBL5313055 | 0.84 | KDM4E (0.52) | HCRTR1KDM4EGLAHTTKMT2A | |
| SCHEMBL5309106 | 0.83 | HPGD (0.41) | SCDF2R | |
| SCHEMBL5312923 | 0.81 | NPC1 (0.44) | KDM4EKMT2ASMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL5313034 | 0.80 | MGLL (0.45) | KDM4EGLAHTTKMT2ASMN1; SMN2 | |
| SCHEMBL5307724 | 0.75 | USP30 (0.47) | PTGESHCRTR1SCDDPP4DPP7 | |
| SCHEMBL6930440 | 0.73 | LMNA (0.63) | PTGESKDM4EHTTKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007044085-A2 | HETEROARYL COMPOUNDS AND THEIR USES AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2007-04-19 | — | — | WO | disclosed |