Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GPR183 | P32249 | 1/20 | 0.41 |
| ▸ | LSS | P48449 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16990245 | 0.83 | ABL1 (0.44) | ALDH1A1HSD17B10KMT2AKDM4E | |
| SCHEMBL4262633 | 0.82 | LMNA (0.50) | ALDH1A1HSD17B10L3MBTL1MEN1KMT2A | |
| SCHEMBL16990306 | 0.82 | TGM2 (0.52) | HSD17B10KDM4E | |
| SCHEMBL2992907 | 0.80 | USP2 (0.46) | ALDH1A1GAAKDM4E | |
| SCHEMBL2836564 | 0.79 | KMT2A (0.62) | ALDH1A1GAAMEN1KMT2AGPR183 | |
| SCHEMBL5309526 | 0.77 | ALDH1A1 (0.59) | ALDH1A1HSD17B10GAAL3MBTL1MEN1 | |
| SCHEMBL12751738 | 0.77 | HTT (0.52) | ALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL26983350 | 0.76 | LMNA (0.52) | ALDH1A1GAAL3MBTL1MEN1KMT2A | |
| SCHEMBL3636698 | 0.76 | L3MBTL1 (0.42) | ALDH1A1L3MBTL1KDM4E | |
| SCHEMBL1433065 | 0.75 | AKR1C3 (0.66) | ALDH1A1HSD17B10GAAL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007039580-A1 | IMIDAZOLYL-SUBSTITUTED BENZOPHENONE COMPOUNDS | NYCOMED GMBH (DE) | 2007-04-12 | — | — | WO | disclosed |