Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 8/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | HK1 | P19367 | 1/20 | 0.44 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5314252 | 0.94 | PTGDR2 (0.47) | PTGDR2MAPTALDH1A1CA12CA1 | |
| SCHEMBL5311262 | 0.91 | PTGDR2 (0.47) | PTGDR2MAPTALDH1A1CA12CA1 | |
| SCHEMBL5311647 | 0.89 | PTGDR2 (0.62) | PTGDR2FLT1FLT4KDRAKR1B1 | |
| SCHEMBL5307689 | 0.89 | PTGDR2 (0.46) | PTGDR2ALDH1A1CA12CA1CA2 | |
| SCHEMBL5310070 | 0.88 | CA12 (0.43) | PTGDR2MAPTALDH1A1HSD17B10CA12 | |
| SCHEMBL5312658 | 0.88 | MAPT (0.51) | PTGDR2MAPTALDH1A1CA12CA1 | |
| SCHEMBL5313784 | 0.88 | USP2 (0.45) | PTGDR2MAPTTP53ALDH1A1CA12 | |
| SCHEMBL5310476 | 0.85 | ALDH1A1 (0.46) | PTGDR2KMT2AMAPTALDH1A1MEN1 | |
| SCHEMBL5310742 | 0.82 | PTGDR2 (0.60) | PTGDR2FLT1FLT4KDRAKR1B1 | |
| SCHEMBL5313192 | 0.82 | PTGDR2 (0.48) | PTGDR2KMT2AMAPTHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007045867-A1 | 3 -AMINOINDOLE COMPOUNDS AS CRTH2 RECEPTOR LIGANDS | ARGENTA DISCOVERY LIMITED (GB) | 2007-04-26 | — | — | WO | disclosed |