Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 18/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 18/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 18/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 17/20 | 0.43 |
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5379498 | 0.85 | CCR1 (0.40) | OPRM1OPRK1OPRD1CCR1 | |
| SCHEMBL5312337 | 0.84 | CCR1 (0.48) | OPRM1OPRK1OPRD1CCR1 | |
| SCHEMBL5307635 | 0.84 | CCR1 (0.39) | OPRM1OPRK1OPRD1CCR1 | |
| SCHEMBL4019904 | 0.81 | CCR1 (0.53) | CCR1 | |
| SCHEMBL5313190 | 0.80 | CCR1 (0.37) | CCR1 | |
| SCHEMBL5362249 | 0.80 | CCR1 (0.39) | CCR1 | |
| SCHEMBL5311863 | 0.79 | CCR1 (0.42) | OPRL1CCR1 | |
| SCHEMBL5310532 | 0.78 | F10 (0.38) | CCR1 | |
| SCHEMBL4019925 | 0.78 | CCR1 (0.40) | CCR1 | |
| SCHEMBL5314510 | 0.77 | HSD11B1 (0.48) | CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007073432-A2 | PIPERIDINE DERIVATIVES AND METHODS OF USE | CHEMOCENTRYX, INC. (US) | 2007-06-28 | — | — | WO | disclosed |
| WO-2007044804-A2 | PIPERIDINE DERIVATIVES AND METHODS OF USE | CHEMOCENTRYX, INC. (US) | 2007-04-19 | — | — | WO | disclosed |