Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 11/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.36 |
| ▸ | MC4R | P32245 | 1/20 | 0.33 |
| ▸ | MC5R | P33032 | 1/20 | 0.33 |
| ▸ | MC3R | P41968 | 1/20 | 0.33 |
| ▸ | MC1R | Q01726 | 1/20 | 0.33 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5379498 | 0.93 | CCR1 (0.40) | CCR1OPRM1OPRD1OPRK1SLC22A1 | |
| SCHEMBL5307882 | 0.84 | OPRM1 (0.43) | CCR1OPRM1OPRD1OPRK1 | |
| SCHEMBL5314510 | 0.78 | HSD11B1 (0.48) | CCR1 | |
| SCHEMBL4449383 | 0.78 | CCR1 (0.63) | CCR1KCNH2 | |
| SCHEMBL5312345 | 0.78 | HSD11B1 (0.49) | CCR1 | |
| SCHEMBL5308835 | 0.77 | CCR1 (0.40) | CCR1OPRM1 | |
| SCHEMBL5313011 | 0.76 | ALDH1A1 (0.49) | CCR1 | |
| SCHEMBL5381831 | 0.76 | HSD11B1 (0.39) | CCR1 | |
| SCHEMBL5362249 | 0.76 | CCR1 (0.39) | CCR1SLC6A4KCNH2 | |
| SCHEMBL4019904 | 0.76 | CCR1 (0.53) | CCR1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007044804-A2 | PIPERIDINE DERIVATIVES AND METHODS OF USE | CHEMOCENTRYX, INC. (US) | 2007-04-19 | — | — | WO | disclosed |