Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | ATR | Q13535 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27791873 | 0.86 | PAX8 (0.44) | GAAKMT2ALMNAPOLBPKM | |
| SCHEMBL2034907 | 0.83 | HDAC1 (0.37) | KMT2AMT-CO2MEN1SMN1; SMN2MAPT | |
| SCHEMBL3634187 | 0.82 | KMT2A (0.43) | GAAKMT2ALMNAPOLBPKM | |
| SCHEMBL23094630 | 0.82 | MT-CO2 (0.38) | KMT2ALMNAALDH1A1MT-CO2TRPA1 | |
| SCHEMBL17166912 | 0.81 | SSTR4 (0.36) | MT-CO2PAX8 | |
| SCHEMBL7696600 | 0.79 | KMT2A (0.41) | GAAKMT2ALMNAPOLBPKM | |
| SCHEMBL3047803 | 0.79 | KCNQ3 (0.43) | GAAKMT2ALMNAPOLBPKM | |
| SCHEMBL19470169 | 0.79 | TRPA1 (0.34) | MT-CO2L3MBTL1TRPA1PAX8 | |
| SCHEMBL13455247 | 0.79 | PAX8 (0.49) | GAAKMT2ALMNAALDH1A1MT-CO2 | |
| SCHEMBL4039542 | 0.78 | P4HTM (0.36) | MT-CO2L3MBTL1TRPA1PAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3286166-B1 | INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | VIIV HEALTHCARE UK NO 5 LTD (GB) | 2020-05-13 | — | — | EP | disclosed |
| US-10221129-B2 | Inhibitors of human immunodeficiency virus replication | VIIV Healthcare UK (No.5) Limited (GB) | 2019-03-05 | — | — | US | disclosed |
| US-20180086697-A1 | INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | BRISTOL-MYERS SQUIBB COMPANY | 2018-03-29 | — | — | US | disclosed |
| EP-3286166-A1 | INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | VIIV Healthcare UK (No.5) Limited (GB) | 2018-02-28 | — | — | EP | disclosed |
| WO-2016172424-A1 | INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | BRISTOL-MYERS SQUIBB COMPANY (US) | 2016-10-27 | — | — | WO | disclosed |
| US-8866139-B2 | Nonvolatile semiconductor memory device | KABUSHIKI KAISHA TOSHIBA (JP) | 2014-10-21 | — | — | US | disclosed |
| EP-2415762-B1 | Method for manufacturing amino-aryl alkyl compounds | SALTIGO GMBH (DE) | 2014-04-23 | — | — | EP | disclosed |
| US-8569823-B2 | Semiconductor device and manufacturing method thereof | KABUSHIKI KAISHA TOSHIBA (JP) | 2013-10-29 | — | — | US | disclosed |
| US-20130234130-A1 | NONVOLATILE SEMICONDUCTOR MEMORY DEVICE | TOSHIBA MEMORY CORPORATION (JP) | 2013-09-12 | — | — | US | disclosed |
| US-8390054-B2 | Semiconductor memory element and semiconductor memory device | KABUSHIKI KAISHA TOSHIBA (JP) | 2013-03-05 | — | — | US | disclosed |
| US-20120071662-A1 | PREPARING AMINOARYLALKYL COMPOUNDS | SALTIGO GMBH (DE) | 2012-03-22 | — | — | US | disclosed |
| US-20120068250-A1 | SEMICONDUCTOR DEVICE AND MANUFACTURING METHOD THEREOF | TOSHIBA MEMORY CORPORATION (JP) | 2012-03-22 | — | — | US | disclosed |
| EP-2415762-A2 | Method for manufacturing amino-aryl alkyl compounds | Saltigo GmbH (DE) | 2012-02-08 | — | — | EP | disclosed |
| US-20110241101-A1 | SEMICONDUCTOR MEMORY ELEMENT AND SEMICONDUCTOR MEMORY DEVICE | KABUSHIKI KAISHA TOSHIBA (JP) | 2011-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120071662-A1 | PREPARING AMINOARYLALKYL COMPOUNDS | CYP3A5, QDPR, AAAS | GAA 1757/4885KMT2A 1559/4885LMNA 1396/4885 |
| US-10221129-B2 | Inhibitors of human immunodeficiency virus replication | EIF2AK2, POLR2E, POLR2H | GAA 278/4885KMT2A 3450/4885LMNA 3667/4885 |
| US-20180086697-A1 | INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | EIF2AK2, POLR2E, POLR2H | GAA 278/4885KMT2A 3450/4885LMNA 3667/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.