Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 5/20 | 0.42 |
| ▸ | HTR7 | P34969 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | DRD3 | P35462 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4520493 | 0.85 | RAB9A (0.51) | RAB9AHTR1AHTR7NPC1MEN1 | |
| SCHEMBL5306802 | 0.84 | ADRA1A (0.49) | RAB9ADRD2DRD3 | |
| SCHEMBL6213257 | 0.83 | HTR1A (0.54) | HTR1AHTR7DRD2DRD3MEN1 | |
| Hydrochloric Acid SCHEMBL6215943 | 0.82 | HTR1A (0.53) | HTR1AHTR7DRD2DRD3MEN1 | |
| SCHEMBL5810923 | 0.78 | RAB9A (0.42) | RAB9AHTR1AHTR7NPC1DRD2 | |
| SCHEMBL4521606 | 0.75 | RAB9A (0.50) | RAB9AHTR1AHTR7DRD2MEN1 | |
| SCHEMBL4521906 | 0.75 | MEN1 (0.40) | RAB9AHTR1AHTR7NPC1MEN1 | |
| SCHEMBL5310370 | 0.74 | ADRA1A (0.50) | RAB9ADRD2DRD3 | |
| Hydrochloric Acid SCHEMBL4526875 | 0.74 | RAB9A (0.49) | RAB9AHTR1AHTR7DRD2MEN1 | |
| Hydrochloric Acid SCHEMBL4533811 | 0.74 | MEN1 (0.40) | RAB9AHTR1AHTR7NPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007029156-A2 | ISOINDOLEDIONE DERIVATIVES AS ADRENERGIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2007-03-15 | — | — | WO | disclosed |