Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 5/20 | 0.49 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.49 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5310370 | 0.90 | ADRA1A (0.50) | ADRA1AADRA1DADRA1BDRD2DRD3 | |
| SCHEMBL5325863 | 0.87 | DRD2 (0.59) | ADRA1AADRA1DADRA1BDRD2DRD3 | |
| SCHEMBL5328407 | 0.85 | SLC6A4 (0.55) | ADRA1AADRA1DADRA1BDRD2DRD3 | |
| SCHEMBL4520493 | 0.85 | RAB9A (0.51) | ADRA1AADRA1DADRA1BRAB9A | |
| SCHEMBL5329403 | 0.85 | ADRA1A (0.65) | ADRA1AADRA1DADRA1BDRD2DRD3 | |
| SCHEMBL5310907 | 0.84 | RAB9A (0.46) | DRD2DRD3RAB9A | |
| SCHEMBL6213257 | 0.83 | HTR1A (0.54) | ADRA1AADRA1DADRA1BDRD2DRD3 | |
| Hydrochloric Acid SCHEMBL6215943 | 0.82 | HTR1A (0.53) | ADRA1AADRA1DADRA1BDRD2DRD3 | |
| SCHEMBL5810923 | 0.78 | RAB9A (0.42) | DRD2DRD3RAB9A | |
| SCHEMBL5308285 | 0.77 | DRD2 (0.58) | ADRA1AADRA1DADRA1BDRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007029156-A2 | ISOINDOLEDIONE DERIVATIVES AS ADRENERGIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2007-03-15 | — | — | WO | claimed |
| WO-2007029156-A2 | ISOINDOLEDIONE DERIVATIVES AS ADRENERGIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2007-03-15 | — | — | WO | disclosed |