Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE1B | Q01064 | 2/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | CDK4 | P11802 | 5/20 | 0.33 |
| ▸ | CCND3 | P30281 | 4/20 | 0.33 |
| ▸ | CDK6 | Q00534 | 4/20 | 0.33 |
| ▸ | CDK1 | P06493 | 3/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | MERTK | Q12866 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.32 |
| ▸ | DYRK2 | Q92630 | 2/20 | 0.32 |
| ▸ | CCND1 | P24385 | 2/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | CDK7 | P50613 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5315261 | 0.87 | BDKRB1 (0.37) | CNR2GRIN2BCDK4CCND3CDK6 | |
| SCHEMBL5311867 | 0.86 | MERTK (0.45) | CDK4CCND3CDK6CDK1MET | |
| SCHEMBL5313507 | 0.86 | DYRK2 (0.45) | CDK4CCND3CDK6CDK1MET | |
| SCHEMBL5336063 | 0.85 | GRM2 (0.37) | GRM2CNR2CDK4CCND3CDK6 | |
| SCHEMBL5315552 | 0.78 | BDKRB1 (0.40) | GRM2CNR2CDK4CCND3CDK6 | |
| SCHEMBL5311883 | 0.77 | TNIK (0.45) | GRM2CDK4CCND3CDK6CDK1 | |
| SCHEMBL5314023 | 0.76 | KDR (0.47) | CDK1METMERTKCDK2CDK9 | |
| SCHEMBL5333911 | 0.76 | MERTK (0.38) | GRM2METMERTKTRPV1CCNT1 | |
| SCHEMBL5334782 | 0.75 | MERTK (0.43) | METMERTK | |
| SCHEMBL5312754 | 0.73 | DYRK2 (0.49) | CDK4CCND3CDK6CCNA2DYRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007058482-A1 | NOVEL INHIBITORS OF PROTEIN KINASE | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | claimed |
| WO-2007058482-A1 | NOVEL INHIBITORS OF PROTEIN KINASE | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | disclosed |