Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | CDC25B | P30305 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | CDC25A | P30304 | 1/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9450667 | 0.83 | ALDH1A1 (0.76) | ALDH1A1KMT2ACYP3A4CYP2C9AKR1C3 | |
| SCHEMBL31333081 | 0.82 | ALDH1A1 (1.00) | ALDH1A1KMT2ACYP3A4CYP2C9AKR1C3 | |
| SCHEMBL1786654 | 0.82 | ALDH1A1 (1.00) | ALDH1A1KMT2ACYP3A4CYP2C9AKR1C3 | |
| SCHEMBL4723682 | 0.81 | POLB (0.74) | ALDH1A1KMT2ACYP3A4CYP2C9AKR1C3 | |
| SCHEMBL9618894 | 0.81 | GABRA1 (0.59) | ALDH1A1KMT2ACYP2C9ATMHPGD | |
| Salicylic Acid SCHEMBL9678811 | 0.81 | ALDH1A1 (0.62) | ALDH1A1KMT2ACYP3A4CYP2C9HSD17B10 | |
| SCHEMBL10421181 | 0.81 | KMT2A (0.51) | ALDH1A1KMT2ACYP3A4CYP2C9AKR1C3 | |
| SCHEMBL29378415 | 0.79 | KMT2A (0.68) | ALDH1A1KMT2ACYP3A4CYP2C9AKR1C3 | |
| SCHEMBL7001733 | 0.79 | KMT2A (0.68) | ALDH1A1KMT2ACYP3A4CYP2C9AKR1C3 | |
| SCHEMBL28268608 | 0.79 | KMT2A (0.68) | ALDH1A1KMT2ACYP3A4CYP2C9AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007044184-A1 | WATER SOLUBLE PHOTOINITIATOR | ALBEMARLE CORPORATION (US) | 2007-04-19 | — | — | WO | disclosed |
| US-20030207889-A1 | Hydroxamic and carboxylic acid derivatives having MMP and TNF inhibitory activity | OWEN DAVID ALAN (GB) | 2003-11-06 | — | — | US | disclosed |
| US-6566384-B1 | For therapy of cancer, inflammation and inflammatory diseases, tissue degeneration, periodontal disease, ophthalmological disease, dermatological disorders, fever, cardiovascular effects, haemorrhage, coagulation and acute phase response | DARWIN DISCOVERY LTD. (GB) | 2003-05-20 | — | — | US | disclosed |
| US-6118001-A | ANTICANCER AGENT; ANTIARTHRITIC AGENT | DARWIN DISCOVERY, LTD. (GB) | 2000-09-12 | — | — | US | disclosed |
| CN-1227540-A | Hydroxamic and carboxylic acid derivatives having MMP and TNF inhibitory activity | DARWIN DISCOVERY CO LTD (GB) | 1999-09-01 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030207889-A1 | Hydroxamic and carboxylic acid derivatives having MMP and TNF inhibitory activity | MMP13, MMP2, MMP9 | ALDH1A1 408/4885KMT2A 1581/4885CYP3A4 2261/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.