Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 5/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ESRRA | P11474 | 1/20 | 0.32 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5306910 | 0.80 | ESRRA (0.36) | MAPTKDM4EGAAESRRADCTPP1 | |
| SCHEMBL5308125 | 0.72 | ESRRA (0.43) | ALDH1A1MAPTKDM4EGAASMN1; SMN2 | |
| SCHEMBL5306918 | 0.71 | MAPT (0.46) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL5313528 | 0.69 | ALDH1A1 (0.45) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL5306577 | 0.66 | CYP11B1 (0.41) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL5306582 | 0.65 | MAPT (0.41) | MAPTLMNASMN1; SMN2ESRRAUSP2 | |
| SCHEMBL5306917 | 0.64 | PHGDH (0.43) | MAPTESRRA | |
| SCHEMBL5326935 | 0.64 | POLB (0.35) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL5338160 | 0.64 | CYP2C19 (0.32) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL4739693 | 0.63 | TOP1 (0.37) | MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007034279-A2 | C3A ANTAGONISTS AND PHARMACEUTICAL COMPOSITIONS THEREOF | PFIZER PRODUCTS INC. (US) | 2007-03-29 | — | — | WO | claimed |
| WO-2007034279-A2 | C3A ANTAGONISTS AND PHARMACEUTICAL COMPOSITIONS THEREOF | PFIZER PRODUCTS INC. (US) | 2007-03-29 | — | — | WO | disclosed |