Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.35 |
| ▸ | PHGDH | O43175 | 5/20 | 0.34 |
| ▸ | ALPL | P05186 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | ESRRA | P11474 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | PPARD | Q03181 | 2/20 | 0.33 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | ASIC1 | P78348 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5326930 | 0.72 | MAPT (0.43) | POLBMEN1KMT2AMALT1MAPT | |
| SCHEMBL5306917 | 0.71 | PHGDH (0.43) | PHGDHALPLCA9ESRRAMAPT | |
| SCHEMBL5304367 | 0.70 | ALDH1A1 (0.44) | POLBMEN1KMT2AMALT1ESRRA | |
| SCHEMBL5308125 | 0.68 | ESRRA (0.43) | ALPLCA9ESRRAMAPTTP53 | |
| SCHEMBL5306918 | 0.67 | MAPT (0.46) | MEN1KMT2AESRRAMAPTTP53 | |
| SCHEMBL5306910 | 0.66 | ESRRA (0.36) | PHGDHALPLCA9ESRRAMAPT | |
| SCHEMBL5306317 | 0.65 | MAPT (0.45) | POLBMEN1KMT2AMAPTLMNA | |
| SCHEMBL5306577 | 0.65 | CYP11B1 (0.41) | MEN1KMT2AALPLCA9ESRRA | |
| SCHEMBL5301960 | 0.65 | TSHR (0.55) | POLBMEN1KMT2AMAPTLMNA | |
| SCHEMBL5311060 | 0.65 | MAPT (0.49) | POLBMEN1KMT2AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007034279-A2 | C3A ANTAGONISTS AND PHARMACEUTICAL COMPOSITIONS THEREOF | PFIZER PRODUCTS INC. (US) | 2007-03-29 | — | — | WO | disclosed |