Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 4/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HPGDS | O60760 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5493321 | 0.86 | DCTPP1 (0.44) | ALDH1A1KDM4ESMN1; SMN2TP53HPGD | |
| SCHEMBL5309093 | 0.82 | ALDH1A1 (0.51) | ALDH1A1KDM4ESMN1; SMN2MAPK1RAB9A | |
| SCHEMBL5311547 | 0.82 | LMNA (0.46) | ALDH1A1KDM4ESMN1; SMN2MAPK1RAB9A | |
| SCHEMBL5309649 | 0.80 | SCD (0.57) | ALDH1A1KDM4ESMN1; SMN2MAPK1RAB9A | |
| SCHEMBL5307062 | 0.79 | SCD (0.51) | ALDH1A1KDM4ESMN1; SMN2MAPK1RAB9A | |
| SCHEMBL5307475 | 0.79 | CA2 (0.41) | ALDH1A1KDM4ESMN1; SMN2MAPK1RAB9A | |
| SCHEMBL5312323 | 0.76 | SCD (0.48) | ALDH1A1KDM4ESMN1; SMN2MAPK1RAB9A | |
| SCHEMBL5309833 | 0.74 | SCD (0.53) | — | |
| SCHEMBL5309660 | 0.73 | SCD (0.56) | ALDH1A1SMN1; SMN2RAB9ALMNA | |
| SCHEMBL5309872 | 0.73 | SCD (0.49) | ALDH1A1KDM4EMAPK1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007046867-A2 | PIPERIDINE DERIVATIVES AND THEIR USES AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2007-04-26 | — | — | WO | disclosed |