Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | CCR1 | P32246 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2991986 | 0.77 | TMEM97 (0.51) | — | |
| SCHEMBL5312589 | 0.74 | PDF (0.36) | CCR1GAA | |
| SCHEMBL586708 | 0.73 | ALDH1A1 (0.42) | NPC1ALOX15MAPTALDH1A1CYP2C19 | |
| SCHEMBL5316207 | 0.73 | CPT1A (0.40) | — | |
| SCHEMBL22705477 | 0.72 | LMNA (0.46) | RIPK1CCR1LMNAHSD17B10ALOX15 | |
| SCHEMBL16992168 | 0.72 | EPHX2 (0.34) | GAALMNAHPGDHSD17B10ALOX15 | |
| SCHEMBL3842757 | 0.72 | CCR1 (0.65) | CCR1GAAHPGDTP53HSD11B1 | |
| SCHEMBL28887472 | 0.69 | PRMT5 (0.52) | RIPK1LMNAALOX15 | |
| SCHEMBL20187290 | 0.69 | PRMT5 (0.52) | RIPK1LMNAALOX15 | |
| SCHEMBL3852873 | 0.68 | RIPK1 (0.33) | RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007067904-A2 | PEPTIDE DEFORMYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-06-14 | — | — | WO | disclosed |