Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 3/20 | 0.35 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | IGF1R | P08069 | 2/20 | 0.34 |
| ▸ | GLS | O94925 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5311989 | 0.91 | LCK (0.37) | ALDH1A1LCKKDM4EMEN1KMT2A | |
| SCHEMBL5312823 | 0.88 | LCK (0.35) | ALDH1A1LCKKDM4EHPGDMEN1 | |
| SCHEMBL5312890 | 0.87 | LCK (0.38) | ALDH1A1LCKKDM4EMEN1KMT2A | |
| SCHEMBL5310797 | 0.86 | LCK (0.35) | ALDH1A1LCKTSHRMEN1KMT2A | |
| SCHEMBL5311529 | 0.85 | LCK (0.39) | ALDH1A1LCKKDM4EMAPTKDR | |
| SCHEMBL14530871 | 0.85 | LCK (0.39) | ALDH1A1SYKLCKKDM4EMEN1 | |
| SCHEMBL5313300 | 0.84 | LCK (0.38) | LCKTSHRKDRIRAK4 | |
| SCHEMBL5312732 | 0.84 | LCK (0.37) | ALDH1A1SYKLCKMEN1KMT2A | |
| SCHEMBL5313272 | 0.84 | LCK (0.38) | ALDH1A1SMN1; SMN2SYKLCKKDM4E | |
| SCHEMBL5310041 | 0.84 | POLB (0.48) | ALDH1A1SMN1; SMN2LCKKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007058482-A1 | NOVEL INHIBITORS OF PROTEIN KINASE | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | claimed |
| WO-2007058482-A1 | NOVEL INHIBITORS OF PROTEIN KINASE | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | disclosed |