Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.30 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 2/20 | 0.30 |
| ▸ | POLB | P06746 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | WNT3A | P56704 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5311989 | 0.89 | LCK (0.37) | LCKMEN1KMT2AIRAK4KDR | |
| SCHEMBL5314725 | 0.87 | LCK (0.33) | LCK | |
| SCHEMBL5312823 | 0.86 | LCK (0.35) | LCKMEN1KMT2AIRAK4KDR | |
| SCHEMBL5314719 | 0.86 | ALDH1A1 (0.35) | LCKMEN1KMT2AIRAK4KDR | |
| SCHEMBL5312890 | 0.85 | LCK (0.38) | LCKMEN1KMT2AIRAK4NR3C2 | |
| SCHEMBL5310041 | 0.83 | POLB (0.48) | LCKMEN1KMT2AKDRPOLB | |
| SCHEMBL5311529 | 0.83 | LCK (0.39) | LCKIRAK4NR3C2KDRMAPT | |
| SCHEMBL14530871 | 0.83 | LCK (0.39) | LCKMEN1KMT2AIRAK4NR3C2 | |
| SCHEMBL5312732 | 0.82 | LCK (0.37) | LCKMEN1KMT2ARXFP1IRAK4 | |
| SCHEMBL5312806 | 0.81 | LCK (0.39) | LCKMEN1KMT2AIRAK4NR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007058482-A1 | NOVEL INHIBITORS OF PROTEIN KINASE | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | claimed |
| WO-2007058482-A1 | NOVEL INHIBITORS OF PROTEIN KINASE | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | disclosed |