Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 10/20 | 0.73 |
| ▸ | LMNA | P02545 | 4/20 | 0.65 |
| ▸ | GAA | P10253 | 2/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | GLA | P06280 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3302462 | 0.93 | LMNA (0.70) | LTA4HLMNAGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL5661423 | 0.91 | LMNA (0.64) | LTA4HLMNAGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL3301180 | 0.89 | LMNA (0.68) | LMNAGAASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL5312324 | 0.88 | LTA4H (0.72) | LTA4HLMNAGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL5311030 | 0.87 | LTA4H (0.61) | LTA4HLMNAGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL5315377 | 0.87 | LTA4H (0.76) | LTA4HLMNAGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL5313298 | 0.86 | ALDH1A1 (0.58) | LTA4HLMNAGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL3045089 | 0.84 | LTA4H (1.00) | LTA4H | |
| SCHEMBL5317908 | 0.84 | LTA4H (1.00) | LTA4HLMNAGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL5313156 | 0.84 | LTA4H (0.71) | LTA4HLMNAGAASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007079003-A2 | AMIDE INHIBITORS OF LEUKOTRIENE A4 HYDROLASE | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-07-12 | — | — | WO | claimed |
| WO-2007079003-A2 | AMIDE INHIBITORS OF LEUKOTRIENE A4 HYDROLASE | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-07-12 | — | — | WO | disclosed |
| US-20070155727-A1 | Amide inhibitors of leukotriene A4 hydrolase | SCHERING AKTIENGESSELLSCHAFT (DE) | 2007-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070155727-A1 | Amide inhibitors of leukotriene A4 hydrolase | LTA4H, LTB4R, LTC4S | LTA4H 1/4885LMNA 1402/4885GAA 1586/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.