Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 4/20 | 0.53 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.50 |
| ▸ | ITGB1 | P05556 | 4/20 | 0.50 |
| ▸ | ITGA5 | P08648 | 4/20 | 0.50 |
| ▸ | ITGAV | P06756 | 3/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.49 |
| ▸ | ITGB5 | P18084 | 2/20 | 0.48 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.48 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.48 |
| ▸ | ITGAL | P20701 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 6/20 | 0.48 |
| ▸ | PPARG | P37231 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3788262 | 0.90 | CA2 (0.62) | SMN1; SMN2MAPK1CA2PTPN1PTPN11 | |
| Trifluoroacetic Acid SCHEMBL4887236 | 0.86 | KDM4E (0.53) | SMN1; SMN2CA2ITGB3ITGB1ITGA5 | |
| Trifluoroacetic Acid SCHEMBL5309778 | 0.85 | HPGD (0.54) | SMN1; SMN2MAPK1ITGB3ITGB1ITGA5 | |
| Trifluoroacetic Acid SCHEMBL5307840 | 0.82 | HTR6 (0.61) | CA2CA1 | |
| SCHEMBL19177180 | 0.81 | MAPK1 (0.57) | SMN1; SMN2MAPK1CA2PTPN1PTPN11 | |
| SCHEMBL28195310 | 0.79 | PPARA (0.55) | SMN1; SMN2MAPK1CA2PTPN1PTPN11 | |
| SCHEMBL6001481 | 0.78 | PTPN1 (0.61) | SMN1; SMN2MAPK1CA2PTPN1PTPN11 | |
| SCHEMBL11512611 | 0.76 | MAPK1 (0.64) | SMN1; SMN2MAPK1CA2PTPN1PTPN11 | |
| Trifluoroacetic Acid SCHEMBL5311009 | 0.76 | ITGB3 (0.54) | SMN1; SMN2MAPK1CA2ITGB3ITGB1 | |
| Trifluoroacetic Acid SCHEMBL7417053 | 0.75 | ITGB3 (0.53) | ITGB3ITGB1ITGA5ITGAVITGB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007047575-A2 | PHARMACOLOGICAL TREATMENTS FOR SLEEP-RELATED BREATHING DISORDERS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2007-04-26 | — | — | WO | disclosed |