Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 7/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | KIF11 | P52732 | 1/20 | 0.50 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.45 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.45 |
| ▸ | ITGAV | P06756 | 3/20 | 0.45 |
| ▸ | ITGA5 | P08648 | 3/20 | 0.45 |
| ▸ | ITGB5 | P18084 | 2/20 | 0.44 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.44 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.44 |
| ▸ | ITGAL | P20701 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GHSR | Q92847 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4887236 | 0.87 | KDM4E (0.53) | HPGDSMN1; SMN2LMNAHTTKIF11 | |
| Trifluoroacetic Acid SCHEMBL5315182 | 0.85 | SMN1; SMN2 (0.54) | SMN1; SMN2ITGB3ITGB1ITGAVITGA5 | |
| Hydrochloric Acid SCHEMBL4640605 | 0.84 | HPGD (0.69) | HPGDSMN1; SMN2LMNAHTTKIF11 | |
| Trifluoroacetic Acid SCHEMBL5307840 | 0.80 | HTR6 (0.61) | GHSR | |
| Trifluoroacetic Acid SCHEMBL7850280 | 0.77 | ALDH1A1 (0.48) | SMN1; SMN2ITGB3ITGB1ITGAVITGA5 | |
| Trifluoroacetic Acid SCHEMBL5311009 | 0.77 | ITGB3 (0.54) | SMN1; SMN2HTTMAPTL3MBTL1ITGB3 | |
| Trifluoroacetic Acid SCHEMBL5758188 | 0.77 | PSIP1 (0.71) | SMN1; SMN2MAPTKDM4EPSIP1 | |
| SCHEMBL1421898 | 0.74 | HPGD (0.65) | HPGDSMN1; SMN2LMNAHTTNR3C2 | |
| SCHEMBL3788262 | 0.74 | CA2 (0.62) | SMN1; SMN2MAPTMAPK1 | |
| Trifluoroacetic Acid SCHEMBL5313227 | 0.73 | MLYCD (0.57) | HPGDSMN1; SMN2HTTMAPTITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007047575-A2 | PHARMACOLOGICAL TREATMENTS FOR SLEEP-RELATED BREATHING DISORDERS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2007-04-26 | — | — | WO | disclosed |