Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 1/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.42 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 3/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.41 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.41 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.41 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.41 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18816709 | 0.81 | IKBKB (0.53) | IKBKBBRD4MKNK1MKNK2PDE4A | |
| SCHEMBL529977 | 0.81 | FABP4 (0.46) | IKBKBBRD4MKNK1MKNK2HTT | |
| SCHEMBL31653573 | 0.81 | FABP4 (0.46) | IKBKBBRD4MKNK1MKNK2HTT | |
| SCHEMBL529917 | 0.79 | IKBKB (0.47) | IKBKBBRD4MKNK1MKNK2PDE4A | |
| SCHEMBL18816703 | 0.79 | IKBKB (0.48) | IKBKBBRD4PDE4APDE4BPDE4C | |
| SCHEMBL9765827 | 0.78 | MAPT (0.49) | IKBKBMKNK1MKNK2PDE4APDE4B | |
| SCHEMBL529975 | 0.78 | FABP3 (0.49) | IKBKBBRD4MKNK1MKNK2HTT | |
| SCHEMBL18816717 | 0.77 | IKBKB (0.58) | IKBKBBRD4PDE4APDE4BPDE4C | |
| SCHEMBL27635473 | 0.76 | ALDH1A1 (0.52) | IKBKBBRD4MKNK1MKNK2TUBB4A | |
| SCHEMBL14610813 | 0.75 | IKBKB (0.63) | IKBKBBRD4PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | claimed |