Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 2/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.46 |
| ▸ | PDE4A | P27815 | 4/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.46 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | NNMT | P40261 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | FABP4 | P15090 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL530231 | 0.83 | MKNK1 (0.43) | BCAT2BRD4KDM4EMEN1KMT2A | |
| SCHEMBL18816709 | 0.80 | IKBKB (0.53) | IKBKBPDE4BPDE4APDE4CPDE4D | |
| SCHEMBL529871 | 0.80 | BCAT2 (0.48) | IKBKBBCAT2BRD4KDM4EFABP4 | |
| SCHEMBL9765827 | 0.79 | MAPT (0.49) | IKBKBPDE4BPDE4APDE4CPDE4D | |
| SCHEMBL18641956 | 0.79 | IKBKB (0.52) | IKBKBPDE4BPDE4APDE4CPDE4D | |
| SCHEMBL6645354 | 0.79 | NNMT (0.49) | IKBKBNNMTKDM4EMEN1KMT2A | |
| SCHEMBL531530 | 0.79 | IKBKB (0.49) | IKBKBPDE4BPDE4APDE4CPDE4D | |
| SCHEMBL27475690 | 0.78 | BCAT2 (0.47) | IKBKBBCAT2BRD4KDM4EFABP4 | |
| SCHEMBL529885 | 0.77 | DHODH (0.46) | IKBKBBCAT2BRD4KDM4EFABP4 | |
| SCHEMBL28471955 | 0.77 | BCAT2 (0.46) | IKBKBBCAT2BRD4KDM4EFABP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | claimed |