Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 9/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.37 |
| ▸ | SCN1A | P35498 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5310221 | 0.80 | KDM4E (0.43) | NOTUMTDO2NPSR1ADORA2ANPC1 | |
| SCHEMBL17407883 | 0.71 | SCN5A (0.47) | NISCHSCN5ACHRNA7SCN2ASCN1A | |
| SCHEMBL16237880 | 0.71 | TDO2 (0.41) | NOTUMNISCHSCN5ATDO2NPSR1 | |
| SCHEMBL7708933 | 0.70 | AURKA (0.46) | NOTUMNISCHSCN5ASCN2ACYP1A2 | |
| SCHEMBL23618148 | 0.70 | SCN5A (0.49) | NISCHSCN5ACHRNA7SCN2ASCN1A | |
| SCHEMBL16052005 | 0.70 | SMN1; SMN2 (0.59) | NISCHSCN5ACHRNA7SCN2ASCN1A | |
| SCHEMBL5310750 | 0.69 | KDM4E (0.36) | NOTUMSMN1; SMN2 | |
| SCHEMBL23618149 | 0.68 | MPL (0.55) | NISCHSCN5ASCN2ASCN1ANPSR1 | |
| SCHEMBL27675967 | 0.67 | CHRNA7 (0.62) | CHRNA7ADORA2ACYP1A2NPC1ADORA3 | |
| SCHEMBL1242144 | 0.67 | KIF11 (0.52) | NOTUMNISCHSCN5ASCN2ASCN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0816347-B1 | Ammonium oxazole- and amino oxazolium intermediates, methods for their preparation and their use in the manufacture of insecticidal, acaricidal and nematocidal arylpyrrole derivatives | BASF AG (DE) | 2007-06-20 | — | — | EP | claimed |
| US-5945538-A | Ammonium oxazole and amino oxazolium intermediates, methods for the preparation thereof and the use therefor in the manufacture of insecticidal arylpyrroles | AMERICAN CYANAMID COMPANY (US) | 1999-08-31 | — | — | US | claimed |
| EP-0816347-A1 | Ammonium oxazole- and amino oxazolium intermediates, methods for their preparation and their use in the manufacture of insecticidal, acaricidal and nematocidal arylpyrrole derivatives | American Cyanamid Company (US) | 1998-01-07 | — | — | EP | claimed |
| EP-0816347-B1 | Ammonium oxazole- and amino oxazolium intermediates, methods for their preparation and their use in the manufacture of insecticidal, acaricidal and nematocidal arylpyrrole derivatives | BASF AG (DE) | 2007-06-20 | — | — | EP | disclosed |
| US-5945538-A | Ammonium oxazole and amino oxazolium intermediates, methods for the preparation thereof and the use therefor in the manufacture of insecticidal arylpyrroles | AMERICAN CYANAMID COMPANY (US) | 1999-08-31 | — | — | US | disclosed |
| US-5925773-A | Ammonium oxazole and amino oxazolium intermediates, methods for the preparation thereof and the use thereof in the manufacture of insecticidal arylpyrroles | AMERICAN CYANAMID COMPANY (US) | 1999-07-20 | — | — | US | disclosed |
| EP-0816347-A1 | Ammonium oxazole- and amino oxazolium intermediates, methods for their preparation and their use in the manufacture of insecticidal, acaricidal and nematocidal arylpyrrole derivatives | American Cyanamid Company (US) | 1998-01-07 | — | — | EP | disclosed |