Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | IL2 | P60568 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11417230 | 0.84 | STAT3 (0.49) | MEN1KMT2AATMMAPTRAB9A | |
| SCHEMBL4157950 | 0.77 | RORC (0.37) | MEN1KMT2ARAB9ALMNASTAT3 | |
| SCHEMBL8657856 | 0.77 | KMT2A (0.59) | MEN1KMT2AATMMAPTRAB9A | |
| SCHEMBL8114922 | 0.76 | ALOX15 (0.45) | MAPTALOX15RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL352658 | 0.75 | MEN1 (0.54) | MEN1KMT2AATMMAPTUSP2 | |
| SCHEMBL29608194 | 0.75 | MEN1 (0.54) | MEN1KMT2AATMMAPTUSP2 | |
| SCHEMBL8660904 | 0.75 | KMT2A (0.64) | MEN1KMT2AATMMAPTUSP2 | |
| SCHEMBL8658188 | 0.75 | MEN1 (0.56) | MEN1KMT2AATMMAPTUSP2 | |
| SCHEMBL8656132 | 0.75 | NPC1 (0.59) | MEN1KMT2AATMMAPTUSP2 | |
| SCHEMBL11417357 | 0.74 | MEN1 (0.48) | PYGLMEN1KMT2AMAPTUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007066496-A1 | BENZOYLUREA COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-06-14 | — | — | WO | disclosed |