Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5316242 | 0.89 | ABCB1 (0.49) | ABCB1HPGDABCG2MEN1L3MBTL1 | |
| SCHEMBL5316942 | 0.88 | LTA4H (0.46) | ABCB1HPGDABCG2L3MBTL1SMN1; SMN2 | |
| SCHEMBL5319733 | 0.87 | POLB (0.48) | HPGDKMT2AHTTPOLBALDH1A1 | |
| SCHEMBL5343106 | 0.86 | KCNH2 (0.48) | ABCB1HPGDABCG2KMT2APOLB | |
| SCHEMBL5314570 | 0.86 | HTR1A (0.48) | HPGDMEN1KMT2AHTTPOLB | |
| SCHEMBL5316192 | 0.85 | HTT (0.52) | HPGDMEN1KMT2AHTTPOLB | |
| SCHEMBL5315867 | 0.83 | ERCC1 (0.44) | HPGDMEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL5316212 | 0.83 | KCNH2 (0.46) | KMT2ASMN1; SMN2POLBALDH1A1KCNH2 | |
| SCHEMBL5317453 | 0.83 | KMT2A (0.48) | KMT2ASMN1; SMN2POLBALDH1A1KCNH2 | |
| SCHEMBL4125747 | 0.83 | KCNH2 (0.48) | L3MBTL1KCNH2KCNJ1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007069986-A1 | NEW OXABISPIDINE COMPOUNDS FOR THE TREATMENT OF CARDIAC ARRHYTHMIAS | ASTRAZENECA AB (SE) | 2007-06-21 | — | — | WO | disclosed |