Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC1 | P07992 | 1/20 | 0.44 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | KCNJ1 | P48048 | 3/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 4/20 | 0.39 |
| ▸ | DRD3 | P35462 | 4/20 | 0.39 |
| ▸ | CLPP | Q16740 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5319733 | 0.91 | POLB (0.48) | HTTKDM4EALDH1A1GLAHPGD | |
| SCHEMBL5318523 | 0.88 | HTR1A (0.43) | ERCC1ERCC4HTTKDM4EALDH1A1 | |
| SCHEMBL5316192 | 0.87 | HTT (0.52) | HTTKDM4EALDH1A1GLAHPGD | |
| SCHEMBL5314874 | 0.87 | POLB (0.54) | HTTKDM4EALDH1A1GLAHPGD | |
| SCHEMBL5317453 | 0.86 | KMT2A (0.48) | ALDH1A1KCNJ1KCNH2POLBSMN1; SMN2 | |
| SCHEMBL5316522 | 0.85 | POLB (0.43) | HPGDTSHRKCNJ1KCNH2POLB | |
| SCHEMBL5314570 | 0.85 | HTR1A (0.48) | HTTKDM4EALDH1A1GLAHPGD | |
| SCHEMBL5315934 | 0.85 | MCHR1 (0.48) | KDM4EALDH1A1TSHRKCNH2POLB | |
| SCHEMBL5315892 | 0.85 | POLB (0.45) | HPGDKCNJ1KCNH2POLBDRD2 | |
| SCHEMBL5331515 | 0.84 | LMNA (0.50) | ALDH1A1TSHRHSD17B10KCNH2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007069986-A1 | NEW OXABISPIDINE COMPOUNDS FOR THE TREATMENT OF CARDIAC ARRHYTHMIAS | ASTRAZENECA AB (SE) | 2007-06-21 | — | — | WO | disclosed |